Clinical trial · Observational
Differences in Immunologic Response to Cryoablation Versus Radiofrequency Ablation in the Treatment of Renal Cell Carcinoma
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): not enough participants
Summary
Brief summary (as posted)
The purpose of this study is to compare changes in the body's self-defense (immune response) after two different treatments for small kidney tumors: 1) Cryoablation (freezing) therapy in which the tumor and a margin of normal kidney tissue are frozen and thawed twice with a needle probe and 2) radiofrequency ablation (RFA) in which radiofrequency energy delivered through a needle probe is used to heat tissue and thereby destroy a tumor.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Immune Response to 3 Approaches | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Adults 18-99
- description
- Adults who are undergoing cryoablation
Primary outcomes (1)
- measure
- Immune Response to Cryoablation, RFA and Laparoscopic Partial Nephrectomy
- timeFrame
- 4 years
- description
- The number of leukocytes found in the tissues cryoablation, radiofrequency ablation, or laparoscopic partial nephrectomy (control)
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * You are eligible to participate in this study if you are an adult (older than 18 years) * Diagnosed with renal cell cancer 1-3 centimeters in size on the CT scan. Exclusion Criteria: * You are not eligible to participate in this study if you are immune compromised (chemotherapy,corticosteroid use, HIV \[as documented in your medical record\], etc.) * Have an autoimmune disorders (Rheumatoid arthritis, Crohn's disease, etc) * Have a tumor larger than 4 cm * Are pregnant.
References
Publications (0)
Data not yet available