Clinical trial · Interventional
Evaluation of Endorings-2-assisted Colonoscopy: a New Accessory for Improvement of Adenoma Detection Rate?
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Screening colonoscopy for colorectal cancer is essential to diagnose and remove adenomas, precancerous stages of colorectal cancer. Unfortunately approximately 25 % of all adenomas are missed during the examination. Recently a new colonoscopy accessory, the Endorings-2 (EndoAid Ltd., Casearea, Israel), has been designed to improved the detection of adenomas during colonoscopy (adenoma detection rate). Endorings-2 is a silicone-rubber device that is fitted on the colonoscope and is equipped with circular flexible silicon rings mechanically stretching the colonic folds during withdrawal. This study aims to evaluate the efficacy of Endorings-2 to improve the adenoma detection rate in a prospective, blinded clinical trial. 292 patients with an indication for a screening colonoscopy shall be included (1:1 randomization in standard colonoscopy versus Endorings-2-assisted colonoscopy).
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colonic Adenoma | Colon Adenoma | ALIAS | 0.90 |
| Colonic Neoplasms | Colon Neoplasm | ALIAS | 0.90 |
| Colonic Polyp | — | UNRESOLVED | — |
| Colonoscopy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endorings-2 | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Endorings-assisted screening colonoscopy
- description
- 146 patients with an indication for screening endoscopy will receive an Endorings-2-assisted colonoscopy.
- interventionNames
- Device: Endorings-2
- type
- NO_INTERVENTION
- label
- Standard screening colonoscopy
- description
- 146 patients with an indication for screening endoscopy will receive a standard colonoscopy.
Primary outcomes (1)
- measure
- Evaluation of the adenoma detection rate during screening colonoscopy
- timeFrame
- Intraoperative. Adenomas detected directly during the examination.
- description
- The primary outcome of this study is the adenoma detection rate of the standard colonoscopy in comparison to the Endorings-assisted colonoscopy.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Patients with an indication for a screening colonoscopy. Exclusion Criteria: * Patients under 18 years, pregnancy * Patients with prior colectomy or partial colectomy * Patients with a history of colorectal cancer * Patients with hereditary polyposis syndromes (FAP, HNPCC) * Patients with a stricture of the colon * Patients receiving anticoagulation prohibiting a colonoscopy * inability to have a patient education * bad conditions prohibiting a colonoscopy
References
Publications (0)
Data not yet available