Clinical trial · Interventional
Warm Acupuncture for Breast Cancer Related Lymphedema
Comparison of Effectiveness Between Warm Acupuncture With Local-Distal Points Association and Local Distribution Points Association in Breast Cancer Related Lymphedema Patients: A Multicenter, Randomized, Controlled Clinical Trial
NCT03373474CI-TRIAL-00051654completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to clarify whether local-distal point association is more effective than local point association by warm acupuncture in the management of breast cancer related lymphedema.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Lymphedema | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| local-distal points association | Other | — | UNRESOLVED |
| local distribution points association | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- local distribution points association
- description
- Participants will receive warm acupuncture with the local distribution acupoints association on the affected arm only.
- interventionNames
- Other: local distribution points association
- type
- EXPERIMENTAL
- label
- local-distal points association
- description
- Participants will receive warm acupuncture with the local-distal acupoints association on the affected arm, unaffected arm, abdomen, and legs.
- interventionNames
- Other: local-distal points association
- type
- NO_INTERVENTION
- label
- waiting-list
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * At least 6 months after breast cancer surgery and presents with persistent breast cancer related upper extremity lymphedema for at least 3 months. Upper extremity lymphedema is defined as more than 2cm circumference difference or 5% volume difference between the affected and unaffected arms. * Stage II or III lymphedema according to the 2016 consensus by the international society of lymphology. * Karnofsky Performance Score (KPS) ≥ 70 * Men or women aged 18 to 80 years * Out-patients * Estimated life expectancy \> 6 months Exclusion Criteria: * Bilateral breast cancer related lymphedema * Taking diuretic * History of primary lymphedema * A diagnosis of severe heart, liver, kidney or hematologic disease * Edema caused by upper extremity disability or other conditions such as heart failure, kidney disease or malnutrition * Have hypoproteinemia * Inflammation, scar, or trauma at the site of operation, or other active skin infections * Unable to self-care, had a history of psychological disorders, or unable to communicate * Received lymphedema treatment within the past 1 month * Pregnancy or breastfeeding * The presence of electronic medical device implants * Deny to sign the informed written consent, or unwilling to conform to randomization * Participation in other clinical trials during the study period
References
Publications (1)
- DERIVEDYeh CH, Zhao TY, Zhao MD, Wu Y, Guo YM, Pan ZY, Dong RW, Chen B, Wang B, Wen JR, Li D, Guo Y, Pan XF. Comparison of effectiveness between warm acupuncture with local-distal points combination and local distribution points combination in breast cancer-related lymphedema patients: a study protocol for a multicenter, randomized, controlled clinical trial. Trials. 2019 Jul 5;20(1):403. doi: 10.1186/s13063-019-3491-4. PMID 31277678