Clinical trial · Interventional
Comparative Study of Antiperistaltic vs Isoperistaltic Billroth II + Braun Anastomosis for Postoperative Reflux
A Superiority Study for Postoperative Reflux After Distal Gastrectomy With Antiperistaltic vs Isoperistaltic Billroth II + Braun Anastomosis
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Postoperative gastroesophageal reflux is one of the most common complications of distal gastrectomy. With more attention paid on it by surgeons, several new operation methods have been practised. Among all these, distal gastrctomy with Billroth II + Braun anastomosis was reported to be an useful method to decrease postoperative reflux rate. Meanwhile, the direction of anastomotic peristalsis has also been reported to affect the anastomosis and thus make difference in reflux rate. We design this study to investigate the potential effect and the superiority of antiperistaltic vs isoperistaltic Billroth II + Braun reconstruction in distal gastrectomy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Postoperative Complications | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Antiperistaltic Billroth II + Braun anastomosis | Procedure | — | UNRESOLVED |
| Isoperistaltic Billroth II + Braun anastomosis | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Antiperistaltic
- description
- In this group patients undergo the distal gestrectomy with antiperistaltic Billroth II + Braun anastomosis
- interventionNames
- Procedure: Antiperistaltic Billroth II + Braun anastomosis
- type
- ACTIVE_COMPARATOR
- label
- Isoperistaltic
- description
- In this group patients undergo the distal gestrectomy with isoperistaltic Billroth II + Braun anastomosis
- interventionNames
- Procedure: Isoperistaltic Billroth II + Braun anastomosis
Primary outcomes (1)
- measure
- Postoperative Reflux Rate
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Pathologically diagnosed as gastric cancer before surgery * Clinical staging: cT1-4aN0-3M0 * Postoperative evaluation concluded B-II B anastomosis * Consent assigned Exclusion Criteria: * Diagnosed with other malignancies within 2 years * Gastric cancer with clinical staging: cT4b or M1 * Women with pregnancy or breast-feeding * Emergency procedures * Consent not assigned
References
Publications (2)
- BACKGROUNDCui LH, Son SY, Shin HJ, Byun C, Hur H, Han SU, Cho YK. Billroth II with Braun Enteroenterostomy Is a Good Alternative Reconstruction to Roux-en-Y Gastrojejunostomy in Laparoscopic Distal Gastrectomy. Gastroenterol Res Pract. 2017;2017:1803851. doi: 10.1155/2017/1803851. Epub 2017 Jan 9. PMID 28163716
- BACKGROUNDIn Choi C, Baek DH, Lee SH, Hwang SH, Kim DH, Kim KH, Jeon TY, Kim DH. Comparison Between Billroth-II with Braun and Roux-en-Y Reconstruction After Laparoscopic Distal Gastrectomy. J Gastrointest Surg. 2016 Jun;20(6):1083-90. doi: 10.1007/s11605-016-3138-7. Epub 2016 Apr 11. PMID 27067234