Clinical trial · Interventional
Psychological Intervention Mobile App for Patients With AML
Randomized Study of a Psychological Intervention Mobile Application (App) to Promote Coping in Patients With Acute Myeloid Leukemia (AML)
NCT03372291CI-TRIAL-00079754completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research study is evaluating the impact of a psychological intervention mobile application (app) on the quality of life, mood, and symptoms of patients with acute myeloid leukemia (AML).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Myeloid Leukemia | Acute Myeloid Leukemia | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Psychological intervention | Other | — | UNRESOLVED |
| Usual Care | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Psychological app
- description
- Psychological intervention consist of four components * Supportive psychotherapy interventions to help patients deal with the initial shock of diagnosis, cope with the loss of independence and abrupt life disruptions, and provide validation and reassurance; * Psychoeducation to manage expectations and enhance preparedness for extended hospitalization and mobilize social supports; * Psychosocial skill-building to promote effective coping strategies and facilitate acceptance while living with uncertainty; * Self-care to promote positive health behaviors and enhance patients' sense of control especially as they transition from the hospital to outpatient care. * The psychological intervention will consist of four sessions (20-25 minutes each) that patients will start during their first week of admission for intensive chemotherapy and continue weekly
- interventionNames
- Other: Psychological intervention
- type
- ACTIVE_COMPARATOR
- label
- Usual Care
- description
- * Participants receiving usual care will not have access to the psychological intervention app. -They will receive usual leukemia care with all the supportive care measures instituted by the leukemia team. * Patients in usual care will also meet with the leukemia social worker based on their request or at the discretion of the treating leukemia team
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients (≥18 years). * New diagnosis of acute myeloid leukemia. * Admitted to Massachusetts General Hospital for intensive induction chemotherapy requiring 4-6-week hospitalization. * The ability to provide informed consent. * Ability to comprehend and speak English. Exclusion Criteria: * Significant uncontrolled psychiatric disorder (psychotic disorder, bipolar disorder, * Major depression) or other co-morbid disease (dementia, cognitive impairment), which the treating clinician believes prohibits the ability to participate in study procedures
References
Publications (2)
- DERIVEDJensen-Battaglia M, Sohn MB, Consagra W, Wang Y, Zhang Z, LoCastro M, Davis J, Buettner K, Mortaz S, El-Jawahri AR, Loh KP. Trajectories of physical well-being among adults with acute myeloid leukemia. Blood Adv. 2024 Jun 11;8(11):2612-2621. doi: 10.1182/bloodadvances.2023011804. PMID 38429079
- DERIVEDEl-Jawahri A, Luskin MR, Greer JA, Traeger L, Lavoie M, Vaughn DM, Andrews S, Yang D, Boateng KY, Newcomb RA, Ufere NN, Fathi AT, Hobbs G, Brunner A, Abel GA, Stone RM, DeAngelo DJ, Wadleigh M, Temel JS. Psychological mobile app for patients with acute myeloid leukemia: A pilot randomized clinical trial. Cancer. 2023 Apr 1;129(7):1075-1084. doi: 10.1002/cncr.34645. Epub 2023 Jan 18. PMID 36655338