Clinical trial · Interventional
Conversion Surgery in Stage IV or Unresectable Gastric Cancer
The Multi-national Multi-institutional Phase 2 Trial for Conversion Surgery in Stage IV or Unresectable Gastric Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): no participants enrolled
Summary
Brief summary (as posted)
This study aims to identify the safety and the survival benefit of the conversion surgery in stage IV or unresectable gastric cancer. The study designed single-arm phase II trial. All the patients would undergo curative-intent radical gastrectomy after palliative chemotherapy if the tumor responded to the chemotherapy. Primary endpoint was three-year overall survival. Secondary endpoints included short-term postoperative outcomes within 30 days, three-year relapse free survival, and success rate of conversion surgery (rate of R0 resection).
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Stage IV or Unresectable Gastric Cancer | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Conversion surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Conversion surgery
- description
- Palliative chemotherapy followed by radical gastrectomy
- interventionNames
- Procedure: Conversion surgery
Primary outcomes (1)
- measure
- 3-year overall survival
- timeFrame
- 3 years after the surgery
- description
- 3-year overall survival after conversion surgery
Secondary outcomes (4)
- measure
- Complication
- timeFrame
- 30 days after the surgery
- description
- Short-term complication rate after conversion surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 19 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Gastric adenocarcinoma * Stage IV or unresectable gastric cancer was diagnosed by pre-operative evaluation including endoscopy, endoscopic ultrasound, Computed tomography (CT), Positron emission tomography-computed tomography (PET CT), or staging laparoscopy * Partial or complete response to chemotherapy * Eastern Cooperative Oncology Group (ECOG) score \<3 * Who agreed to enroll the study Exclusion Criteria: * Synchronous or metachronous malignancy * remnant gastric cancer * BMI less than 18.5 * Pregnancy
References
Publications (0)
Data not yet available