Clinical trial · Observational
Sitting Versus Horizontal Position on Craniotomies
The Effects of Sitting Position on the Outcome During Surgery on Posterior Cranial Fossa and Pineal Region
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main objectives of this study are comparison of the incidence of intraoperative air embolism and the extent of blood loss in patients undergoing posterior cranial fossa (PCF) and pineal region (PR) surgeries in sitting and horizontal position. Additionally, the overall treatment outcome, neurological functional outcome, degree of tumor removal, clinical course in the postoperative period, and the patient satisfaction will be compared between the groups.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumor | Brain Neoplasm | ALIAS | 0.90 |
| Craniotomy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgical position | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Sitting Position
- description
- Sitting and semi-sitting
- interventionNames
- Procedure: Surgical position
- label
- Horizontal Position
- description
- Prone, lateral and park bench.
Primary outcomes (1)
- measure
- Incidence of intraoperative air embolism
- timeFrame
- Time of surgery (From surgical wound incision time until wound closure)
- description
- Measured intraoperatively with transesophageal echocardiogram and/or PETCO2 levels
Secondary outcomes (3)
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: * Patients 18 - 75 years old undergoing open posterior cranial fossa and pineal region surgery and diagnosed with space-occupying or vascular lesions willing consent to participate in the study. Exclusion Criteria: * Significant cardio-vascular comorbid conditions (cardiac insufficiency, recent infarction, advanced arterial hypertension) * Advanced chronic respiratory comorbid conditions * Uncorrected hypovolemia, anemia, hypoalbuminemia * De-compensated acid base and electrolyte disorders * Anticoagulated patients and patients with coagulation disorders, deep venous thrombosis (history of deep vein thrombosis or clinically established) * Preoperative evidence of spinal or peripheral nerve dysfunction that may interfere with patient positioning. * Cervical myelopathy * Cervical spine disorders (atlanto-occipital arthritis, previous fractures etc.)
References
Publications (1)
- DERIVEDMavarez-Martinez A, Israelyan LA, Soghomonyan S, Fiorda-Diaz J, Sandhu G, Shimansky VN, Ammirati M, Palettas M, Lubnin AY, Bergese SD. The Effects of Patient Positioning on the Outcome During Posterior Cranial Fossa and Pineal Region Surgery. Front Surg. 2020 Mar 13;7:9. doi: 10.3389/fsurg.2020.00009. eCollection 2020. PMID 32232048