Clinical trial · Interventional
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
Prospective Randomized Controlled Trial of High-Definition White-light Colonoscopy Versus High-Definition White-light Colonoscopy With Endocuff Vision for Endpoints of Procedural Times
NCT03361917CI-TRIAL-00039891completedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Colorectal Adenoma | Colorectal Adenoma | ONTOLOGY_EXACT | 0.98 |
| Colorectal Polyp | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endocuff Vision | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Control Arm (Standard Colonscopy)
- description
- Standard colonoscopy with no device attachments
- type
- EXPERIMENTAL
- label
- Endocuff Vision
- description
- Colonoscopy with Endocuff Vision attached to distal end of scope
- interventionNames
- Device: Endocuff Vision
Primary outcomes (1)
- measure
- Inspection Time Comparisons for Each Method (Standard vs. Endocuff Vision)
- timeFrame
- During the withdrawal portion of the colonoscopy procedure
- description
- Inspection time is time spent actually examining the colon. This was measured with a stopwatch and calculated by subtracting washing, suctioning, polypectomy and biopsy times from total withdrawal time. It was measured during colonoscopy by a study assistant using a stopwatch.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
Show eligibility criteria text
Inclusion Criteria: * Subject referred for a screening or surveillance colonoscopy * Subject is aged 40 years or older * Subject has the ability to provide informed consent Exclusion Criteria: * Prior history of colon cancer * History of inflammatory bowel disease * Prior surgical resection of any part of the colon * Use of antiplatelet agents or anticoagulants that precludes the removal of polyps during the procedure * History of polyposis syndrome or HNPCC * Family history of colon cancer in a first-degree relative \< 60 years or two first degree relatives with colorectal cancer * Inability to provide informed consent
References
Publications (2)
- BACKGROUNDTsiamoulos ZP, Misra R, Rameshshanker R, Elliott TR, Beintaris I, Thomas-Gibson S, Haycock A, Suzuki N, Rees C, Saunders BP. Impact of a new distal attachment on colonoscopy performance in an academic screening center. Gastrointest Endosc. 2018 Jan;87(1):280-287. doi: 10.1016/j.gie.2017.04.001. Epub 2017 Apr 13. PMID 28412271
- DERIVEDRex DK, Slaven JE, Garcia J, Lahr R, Searight M, Gross SA. Endocuff Vision Reduces Inspection Time Without Decreasing Lesion Detection: A Clinical Randomized Trial. Clin Gastroenterol Hepatol. 2020 Jan;18(1):158-162.e1. doi: 10.1016/j.cgh.2019.01.015. Epub 2019 Jan 17. PMID 30659990