Clinical trial · Interventional
Prevention of Mucositis in Patients With Head and Neck Cancer Treated With Radiotherapy
Prevention of Radiation-induced Mucositis in Patients With Head and Neck Cancer Treated With Radiotherapy : A Double-blind Randomized Controlled Trial
NCT03359187CI-TRIAL-00046459completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Prevention of radiation-induced mucositis in patients with head and neck cancer treated with radiotherapy : A Double-blind Randomized Controlled Trial
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adverse Effect of Radiation Therapy | — | UNRESOLVED | — |
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Radiation- Induced Mucositis | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Boesenbergia rotunda | Other | — | UNRESOLVED |
| Clinacanthus nutans | Other | — | UNRESOLVED |
| Normal saline with salt/Soda | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- ACTIVE_COMPARATOR
- label
- Normal saline with salt/Soda
- description
- Normal saline with salt/soda rinse 4 times a day/everyday and for each time 15 ml.
- interventionNames
- Other: Normal saline with salt/Soda
- type
- EXPERIMENTAL
- label
- Clinacanthus nutans
- description
- Clinacanthus nutans in form of mouth wash rinse 4 times a day/everyday and for each time 15 ml.
- interventionNames
- Other: Clinacanthus nutans
- type
- EXPERIMENTAL
- label
- Boesenbergia rotunda
- description
- Boesenbergia rotunda in form of mouth wash 4 times a day/everyday and for each time 15 ml.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Aged 15 years old or older, * Diagnosed with Head and Neck cancer * On treatment of external Radiation therapy Exclusion Criteria: * Pregnant * Previously underwent external Radiation therapy * Illiterate
References
Publications (1)
- DERIVEDKongwattanakul S, Petchann N, Petroch P, Thanthong S, Tungfung S, Chamchod S, Pitiporn S, Nantajit D. Prophylactic management of radiation-induced mucositis using herbal mouthwash in patients with head and neck cancer: an assessor-blinded randomized controlled trial. J Complement Integr Med. 2022 Feb 28;19(3):771-780. doi: 10.1515/jcim-2021-0457. eCollection 2022 Sep 1. PMID 35218685