Clinical trial · Interventional
Cardiac Coherence Combined With Personal Physical Activity in Patients With Cancer
Combination of Cardiac Coherence to Physical Activity
NCT03356171CI-TRIAL-00096158APACCHEcompletedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
APACCHE (Adapted Physical Activity and Cardiac Coherence in HEmatologic patients) study investigates effects of heart rate variability biofeedback training, combined with classical adapted physical activity, on health-related quality of life in patients previously treated for hematologic malignancies. It is a prospective, randomized clinical trial from University Hospital of Reunion Island. The main objective is evaluated with QLQ-C30 survey score differences.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Hematologic Diseases | — | UNRESOLVED | — |
| Physical Activity | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Adapted Physical Activity | Procedure | — | UNRESOLVED |
| Cardiac Coherence | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Cardiac Coherence
- description
- Patients participate to Adapted physical activity sessions and to cardiac coherence sessions
- interventionNames
- Procedure: Cardiac Coherence
- type
- ACTIVE_COMPARATOR
- label
- Adapted Physical Activity
- description
- Patients only participate to Adapted physical activity sessions
- interventionNames
- Procedure: Adapted Physical Activity
Primary outcomes (1)
- measure
- Health-related quality of life
- timeFrame
- on week 12
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * All patients, previously treated and in remission for an Hematologic malignancy, in whom APA is indicated. * Adult patients aged 18-65 yo * Followed at South University Hospital of La Réunion Island * Previously treated for Hematologic Malignancy, and in Remission (complete or partial) * 6 months or less since last treatment * Hemoglobin steady ≥ 90g/L * In whom APA is prescribed * Ability to give oral informed consent * French understanding Exclusion Criteria: * With contraindication for APA * Under anti-arhythmic or beta-blocker drugs * Cardiac insufficiency (Left ventriculi Ejection Fraction less than 40%) * Participation in another trial
References
Publications (1)
- DERIVEDFournie C, Bouscaren N, Dalleau G, Lenclume V, Mohr C, Zunic P, Cabrera Q, Verkindt C. Adapted physical activity and cardiac coherence in hematologic patients (APACCHE): study protocol for a randomized controlled trial. BMC Sports Sci Med Rehabil. 2020 Mar 14;12:18. doi: 10.1186/s13102-020-00170-3. eCollection 2020. PMID 32190333