Clinical trial · Interventional
Stimulation of Acupuncture Points by Athermic Laser Therapy for the Prevention of Chemotherapy Induced Nausea and Vomiting in Children
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Poor control of chemotherapy-induced nausea and vomiting has a major clinical and psychological impact in patients treated with chemotherapy. Metabolic, nutritional and mechanical complications, as well as psychological repercussions, complicate the therapeutic management of the patient and can lead to poor compliance, a deterioration in the general condition or even prolongation of hospitalizations and a delay in the implementation of chemotherapy cures. The control of induced chemo- and radio-induced nausea and vomiting rests above all on their prevention. At present and in most centers, the prevention of nausea and vomiting in the pediatric onco-hematology department of the CHU de Nice is based exclusively on drug treatments, according to a protocol established according to the emetogenic risk of the chemotherapy received. We propose a study evaluating the effectiveness of the stimulation of acupuncture points by low frequency laser therapy associated with antiemetics in the management of chemotherapy induced nausea and vomiting in patients of 2 to 20 years followed in the service of analgesics. pediatric onco-hematology.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chemotherapy-induced Nausea and Vomiting | — | UNRESOLVED | — |
| Children | — | UNRESOLVED | — |
| Malignant Tumor | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| laser therapy | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- Laser then Sham therapy
- description
- 2nd cycle of chemotherapy : administration of laser therapy 3th cycle of chemotherapy : administration of a sham laser according to the same modalities
- interventionNames
- Other: laser therapy
- type
- OTHER
- label
- Sham therapy then laser
- description
- 2nd cycle of chemotherapy : administration of a sham laser 3th cycle of chemotherapy : administration of laser therapy according to the same modalities
- interventionNames
- Other: laser therapy
Primary outcomes (1)
- measure
- The complete response to the preventive treatment of nausea and vomiting
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 2 Years
- Maximum age
- 20 Years
Show eligibility criteria text
Inclusion Criteria: * Diagnosis of malignant pathology with indication of chemotherapy with moderate to severe emetogenic potential * Indication of at least three identical chemotherapy cures * Age between 2 and 20 years * Prescription of an anti emetic protocol * Karnosky / Lansky Index\> 60% Exclusion Criteria: * Proven laser contraindication * Vomiting in the 24 hours before starting treatment * Presenting a brain lesion responsible for nausea and vomiting * Pelvic abdominal irradiation the week before the start of treatment * Treatment with benzodiazepines or opioids the week before treatment * Pregnant women
References
Publications (1)
- RESULTRenaux Torres MC, Bouttefroy S, Letort-Bertrand M, Maurel V, Mouffak S, Scotte F, Slimano F, Treguier P, Dupuis LL, Poiree M, Thouvenin-Doulet S. [Chemotherapy-induced nausea and vomiting in pediatric oncology patients: 2023 recommendations from the Supportive Care Committee of the French Society of Cancer in Children and Adolescents]. Bull Cancer. 2024 Jun;111(6):608-619. doi: 10.1016/j.bulcan.2024.02.017. Epub 2024 Apr 25. French. PMID 38670821