Clinical trial · Observational
Target Therapies Resistance Molecular Profiling in Patients With Neoplastic Disease
Non-interventional Study for the Determination of Molecular Resistance Profiling to Targeted Therapies in Patients With Neoplastic Disease
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The main purpose of this study is to define the molecular profile of selected solid tumors. From each participants will be collected biological materials for molecular analysis, including saliva, blood and vital tumor tissue derived form surgical or biopsy procedures. Whereas possible, vital tumor specimens will be inoculated and propagated in immunocompromised NOD/SCID mice to study the genetic correlations between genetic status and response to target drugs.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumors | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- number of patient correctly sampled
- timeFrame
- through study completion, an average of five years
- description
- number of patients with biological samples idoneous for molecular profiling testing (nucleic acid extraction, protein) over all recruited patients.
Secondary outcomes (1)
- measure
- number of patients with detected genetic alterations that respond to treatments assigned by physician.
- timeFrame
- through study completion, an average of five years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Patients with at least one of the following selected solid tumors: * Colorectal Cancer (primary or with synchronous/metachronous liver metastases) * Prostate Cancer * Head \& Neck Tumors * Gastric Cancer * Glioblastoma * Breast Cancer * Hepatocarcinoma * Biliary Tract Carcinoma * Lung Cancer (primary) * Rare Tumors (incidence ≤ 5x10-6) * Metastatic Sarcoma * Metastatic Melanoma Exclusion Criteria: \-
References
Publications (0)
Data not yet available