Clinical trial · Observational
Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
Comparative Effectiveness of Bronchoscopic Interventions for Malignant Airway Obstruction
NCT03326570CI-TRIAL-00038158completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The goal of this clinical research study is learn about side effects and the success of bronchoscopies when performed in cancer patients with and without symptoms. This is an investigational study. Up to 110 patients will take part in this study. All will be enrolled at MD Anderson.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Medical Data Collection | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Bronchoscopy Data Collection
- description
- Medical information collected after bronchoscopy for up to 2 years.
- interventionNames
- Behavioral: Medical Data Collection
Primary outcomes (1)
- measure
- Time to Any Complication Requiring Treatment
- timeFrame
- 2 years
- description
- Researchers will estimate the hazard function of time to any complications in the framework of competing risks while death is the competing risk.3 Researchers will graphically visualize the hazard function of time to any complications using Kernel smoothing method.
Secondary outcomes (1)
- measure
- Quality-Adjusted Survival
- timeFrame
- 2 years
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: ° All patients undergoing interventional bronchoscopy during the first 12 months will be enrolled, with follow-up occurring out to 2 years from the study startup (the duration of the grant). Exclusion Criteria: * Age less than 18 years, * Inability to participate in telephone follow-up
References
Publications (1)
- DERIVEDOng P, Grosu HB, Debiane L, Casal RF, Eapen GA, Jimenez CA, Noor L, Ost DE. Long-term quality-adjusted survival following therapeutic bronchoscopy for malignant central airway obstruction. Thorax. 2019 Feb;74(2):141-156. doi: 10.1136/thoraxjnl-2018-211521. Epub 2018 Sep 25. PMID 30254139