Clinical trial · Interventional
Flu Vaccine Responses in the Setting of Melanoma Treatment
Influenza Vaccine Responses in the Setting of Melanoma Treatment
NCT03315975CI-TRIAL-00093821active not recruitingPhase 4ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Influenza vaccination is indicated for all adults, but the immunogenicity of vaccination has not been assessed in all situations. We are conducting a prospective unblinded study of influenza vaccine recipients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Viral Vaccines | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Inactivated influenza vaccine | Biological | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Influenza vaccination cohort
- description
- Subjects will receive one dose of seasonal quadrivalent inactivated influenza vaccine intramuscularly for standard of care for prevention of influenza infection.
- interventionNames
- Biological: Inactivated influenza vaccine
Primary outcomes (1)
- measure
- Neutralizing antibody response
- timeFrame
- 21-42 days
- description
- The neutralizing antibody titer will be assessed by measurement of the hemagglutinin-inhibition titer before and after influenza vaccination in order to determine the seroconversion rate. The late blood draw may occur between days 21-42 following vaccination.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * adults capable of providing consent * have a diagnosis of locally advanced or metastatic melanoma Exclusion Criteria: * are allergic to influenza vaccination * have received influenza vaccination within the past 6 months * require prednisone, methotrexate, or other immunosuppressing medications * have HIV infection * have a history of solid organ or bone marrow transplant * require combination immunotherapy * are on other studies requiring blood draws that might exceed 450 mL total during the period of the influenza vaccine study
References
Publications (0)
Data not yet available
No reference posted for this study.