Clinical trial · Observational
Circulating Tumor DNA As Liquid Biopsy in Patients with Stage IV Solid Tumors, a Feasibility Study At MUSC HCC
NCT03302325CI-TRIAL-00080712completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
1. To demonstrate the ability to detect specific cancer mutations in ctDNA isolated from plasma of stage IV cancer patients at HCC. 2. To compare, in each patient, ctDNA longitudinal samples through treatment, and when available, with those of primary tumor and metastasis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumor, Adult | Adult Solid Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| research blood draws | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Stage IV solid tumors
- description
- adult patients with stage IV cancer that are starting a new line of treatment
- interventionNames
- Procedure: research blood draws
Primary outcomes (2)
- measure
- Detecting specific cancer mutations in ctDNA isolated from plasma of stage IV cancer patients at HCC.
- timeFrame
- 24 months
- measure
- Changes in patients' ctDNA longitudinal samples through treatment, and when available, of primary tumor and metastasis.
- timeFrame
- 24 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Confirmed diagnosis of stage IV malignancy, including any advanced solid tumors (including lymphoma) * Eastern Cooperative Oncology Group (ECOG) performance Status (PS) 0-3 * Life expectancy ≥ 3 months * Patients must be able to provide consent * Patients can be enrolled in other interventional clinical trials Exclusion Criteria: \- Age \< 18-year-old
References
Publications (0)
Data not yet available
No reference posted for this study.