Clinical trial · Observational
Primary Liver Cancer Cohort of South China
Factors Influencing the Occurrence and Long-term Survival of Patients With Primary Liver Cancer: A Cohort Study in South China
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This longitudinal observational cohort study was designed to investigate factors that influencing the occurrence and long-term survival of patients with primary liver cancer. Basic informations and detailed diagnosis informations (AJCC/TNM stage, MELD score, Child-Pugh score, and BCLC stage) were collected by professional doctors. Clinical outcomes (death, recurrence, and metastasis) will be followed up every two years after therapy.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Primary Liver Cancer | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Time of Death
- timeFrame
- Up to 10 years
- description
- The exact death time of each participants will be checked in the government medical records system
Secondary outcomes (2)
- measure
- Time of recurrence
- timeFrame
- From date of diagnosis until the date of cancer recurrence or date of death from any cause, whichever came first, assessed up to 10 years
- description
- Time of recurrence will be obtained by telephone interview or medical treatment records
- measure
- Time of metastasis
- timeFrame
- From date of diagnosis until the date of cancer metastasis or date of death from any cause, whichever came first, assessed up to 10 years
- description
- Time of metastasis will be obtained by telephone interview or medical treatment records
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * age 18-80 years * consistent with primary liver cancer diagnostic criteria * first diagnosis (from diagnosis to admission interval of less than a month) * did not do any treatment of liver cancer Exclusion Criteria: * refused to participate in this study * suffering from more than two kinds of primary tumors
References
Publications (2)
- DERIVEDLiu ZY, Yishake D, Fang AP, Zhang DM, Liao GC, Tan XY, Zhang YJ, Zhu HL. Serum choline is associated with hepatocellular carcinoma survival: a prospective cohort study. Nutr Metab (Lond). 2020 Mar 30;17:25. doi: 10.1186/s12986-020-00445-z. eCollection 2020. PMID 32256673
- DERIVEDLiu ZY, Tan XY, Li QJ, Liao GC, Fang AP, Zhang DM, Chen PY, Wang XY, Luo Y, Long JA, Zhong RH, Zhu HL. Trimethylamine N-oxide, a gut microbiota-dependent metabolite of choline, is positively associated with the risk of primary liver cancer: a case-control study. Nutr Metab (Lond). 2018 Nov 20;15:81. doi: 10.1186/s12986-018-0319-2. eCollection 2018. PMID 30479648