Clinical trial · Observational
Oral Cell DNA Adducts in Smokers
Quantitation of Oral Cell DNA Adducts in Smokers
NCT03285893CI-TRIAL-00082455OCDNAcompletedResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
DNA adducts in the oral mucosa cells of 100 smokers from 3 ethnic groups - Native Hawaiians, Whites, and Japanese Americans with differing risks for lung cancer upon cigarette smoking will be quantified. DNA adducts of tobacco smoke carcinogens will be quantified using both targeted and untargeted approaches.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| oral cell DNA adducts | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Native Hawaiian cigarette smokers
- description
- oral cell DNA adducts
- interventionNames
- Other: oral cell DNA adducts
- label
- White (European Americans) cigarette smokers
- description
- oral cell DNA adducts
- interventionNames
- Other: oral cell DNA adducts
- label
- Japanese American cigarette smokers
- description
- oral cell DNA adducts
- interventionNames
- Other: oral cell DNA adducts
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * currently smoke at least 5 cigarettes per day, self-identified Japanese Americans, European Americans, or Native Hawaiians. Exclusion Criteria: * no current use of other nicotine containing products, no acute or uncontrolled medical or psychiatric conditions, no greater than 14 alcoholic drinks per week, not pregnant, not breastfeeding, not currently taking any medications that affect relevant metabolic enzymes, no active infection.
References
Publications (0)
Data not yet available
No reference posted for this study.