Clinical trial · Interventional
Decisions About Cancer Screening in Alzheimer's Disease
NCT03282097CI-TRIAL-00093401DECADcompletedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Decisions about Cancer screening in Alzheimer's Disease (DECAD) study tests if an evidence-based decision aid for dementia caregivers can support decision-making about mammography and improve the quality of medical decision-making about breast cancer screening. This large randomized controlled trial will recruit up to 450 dyads (900 individual participants) of older women with dementia and a family caregiver, for a goal of 426 dyad baselines (852 individual participants).
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Alzheimer Disease | — | UNRESOLVED | — |
| Cancer, Breast | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DECAD decision aid | Behavioral | — | UNRESOLVED |
| Home safety guide | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Mammogram decision aid
- description
- Family caregivers and patients with dementia will be mailed the DECAD decision aid about mammography and breast cancer screening before the patients next PCP visit to test if the aid improves decision making about breast cancer screening in older women with dementia.
- interventionNames
- Behavioral: DECAD decision aid
- type
- ACTIVE_COMPARATOR
- label
- Home safety guide
- description
- Family caregivers and patients with dementia will be mailed a home safety guide, which is a two-page paper pamphlet developed by the American Geriatrics Society Foundation for Health in Aging. It provides tips about important actions older adults can take to prevent falls, poisoning, and bathroom hazards and protection against abuse, fire and other related hazards. We selected the home safety guide to account for the attention given to the intervention group but not to provide information that would bias the control group about mammography.
- interventionNames
- Other: Home safety guide
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 75 Years
Show eligibility criteria text
Patient Inclusion Criteria: * Female and 75 years or older * At least one mammogram in the past five years * Primary care visit scheduled in the next 12 months * Diagnosis of Alzheimer's disease or related dementia as determined by ICD-10 code * Ability to provide informed consent or assent * Ability to communicate in English Patient Exclusion Criteria: * Permanent resident of a nursing facility * Had a mammogram in the past 6 months * Primary care visit scheduled is the first visit with the PCP * Made a decision to stop getting mammograms * History of Atypical Ductal Hyperplasia, lobular carcinoma in situ, ductal carcinoma in situ, or non-invasive breast cancer * Has mild cognitive impairment, serious mental illness such as bipolar or schizophrenia as determined by ICD-10 code Caregiver Inclusion Criteria: * 18 years or older * Primary family caregiver of the patient\* * Must have a telephone * Ability to provide informed consent * Ability to communicate in English Caregiver Exclusion Criteria: * Caregiver is a non-family member who is not a legal Healthcare Power of Attorney * Less than a 7th grade education\*\* * Made a decision that the patient will stop getting mammograms * Has a diagnosis of AD or has a serious mental illness such as bipolar or schizophrenia as determined by ICD-10 code
References
Publications (1)
- DERIVEDFowler NR, Schonberg MA, Sachs GA, Schwartz PH, Gao S, Lane KA, Inger L, Torke AM. Supporting breast cancer screening decisions for caregivers of older women with dementia: study protocol for a randomized controlled trial. Trials. 2018 Dec 12;19(1):678. doi: 10.1186/s13063-018-3039-z. PMID 30541634