Clinical trial · Interventional
Effect of Prevention Education in Caries Formation in Pediatric Patients With Leukemia
Effect of Prevention Education on Factors of Importance in Caries Formation in Pediatric Patients With Leukemia
NCT03281746CI-TRIAL-00043634terminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Slow accrual
Summary
Brief summary (as posted)
This randomized pilot clinical trial studies how well preventive education works in decreasing caries formation in pediatric patients with leukemia. Prevention education may have an effect on factors important in causing cavities in pediatric patients with leukemia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Leukemia | Leukemia | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (5)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Dental Procedure | Procedure | — | UNRESOLVED |
| Educational Intervention (one-on one education) | Other | — | UNRESOLVED |
| Educational Intervention (prevention education) | Other | — | UNRESOLVED |
| Interview | Other | — | UNRESOLVED |
| Survey Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Group I (standard prevention education)
- description
- Patients undergo dental examination at baseline and then receive standard prevention education at diagnosis discussing the effects of prolonged neutropenia on oral hygiene, importance of a regular oral hygiene regimen, and the long term clinical outcomes of oncologic patients. Patients also receive fliers with pictograms describing proper brushing, use of mouth wash, and common oral complications during therapy, as well as a bottle and prescription for chlorhexidine gluconate 0.12% rinse.
- interventionNames
- Procedure: Dental Procedure
- Other: Educational Intervention (prevention education)
- Other: Interview
- Other: Survey Administration
- type
- EXPERIMENTAL
- label
- Group II (standard and one-on-one education, consultation)
- description
- Patients undergo dental examination and receive standard prevention education as in Group I. Patients also receive one-on-one prevention education and counseling with the physician and pediatric dental resident.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 3 Years
- Maximum age
- 12 Years
Show eligibility criteria text
Inclusion Criteria: * Pediatric patients who have been recently diagnosed with leukemia * Patients will also predictably be in primary or mixed dentition * Patients of Virginia Commonwealth University Medical Center Pediatric Hematology Oncology Clinic Exclusion Criteria: * Full permanent dentition * Primary language is not English * Children in the custody of the state with no parent or legal guardian present to sign consent
References
Publications (0)
Data not yet available
No reference posted for this study.