Clinical trial · Interventional
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement
NCT03273348CI-TRIAL-00029422unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Role of Oncoplastic Breast Surgery In Breast Cancer Treatement
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Oncoplastic breast surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- oncoplastic breast surgery
- description
- This study aim to evaluate the outcome on oncological side and patient satisfaction on the aesthetic side with skin-sparing mastectomy and immediate breast reconstruction for patients with early breast cancer .
- interventionNames
- Procedure: Oncoplastic breast surgery
Primary outcomes (1)
- measure
- oncological safety
- timeFrame
- for 2 weaks
- description
- the pathological report postoperative reveals safety free margins
Secondary outcomes (3)
- measure
- postoperative recurrence of malignany
- timeFrame
- assess for 1 year postoperative
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 30 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: * The study will include 30 women with early-stage breast cancer treated at general surgery department, Assuit University Hospitals * For all patients an informed consent for their inclusion in the study including the use of images will be obtained. * Selection criteria include women with a pre-operative diagnosis (clinical examination, imaging and needle biopsy) of Tis, T1 and T2 tumours without extensive skin involvement. Exclusion Criteria: * • contraindaction for general anesthesia * Positive margin requiring mastectomy * Insufficient remaining breast volume * Diffuse microcalcifications * Multicentric tumor? * Inflammatory breast cancer * Previous radiotherapy * Concomitant disease ( Diabetes, smoking )
References
Publications (3)
- BACKGROUNDFerlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer. 2010 Dec 15;127(12):2893-917. doi: 10.1002/ijc.25516. PMID 21351269
- BACKGROUNDVeiga DF, Veiga-Filho J, Ribeiro LM, Archangelo I Jr, Balbino PF, Caetano LV, Novo NF, Ferreira LM. Quality-of-life and self-esteem outcomes after oncoplastic breast-conserving surgery. Plast Reconstr Surg. 2010 Mar;125(3):811-7. doi: 10.1097/PRS.0b013e3181ccdac5. PMID 20195109
- BACKGROUNDLosken A, Dugal CS, Styblo TM, Carlson GW. A meta-analysis comparing breast conservation therapy alone to the oncoplastic technique. Ann Plast Surg. 2014 Feb;72(2):145-9. doi: 10.1097/SAP.0b013e3182605598. PMID 23503430