Clinical trial · Observational
Age Gene/Environment Susceptibility Reykjavik Study
Association of Pre-diagnostic Vitamin D Levels and Survival in Older Individuals With Cancer
NCT03269656CI-TRIAL-00029384AGEScompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
5764 men and women in Iceland, aged 66 to 96 years entered the Ages Gene/Environment Susceptibility (AGES) - Reykjavik Study. Serum 25(OH)D was measured in 5,519 of all 5,764 (96%) participants at study entry in year 2002 through 2006. The main emphasis was on exploring whether pre-diagnostic serum levels of 25(OH)D were associated with survival after cancer diagnosis.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (1)
- label
- AGES-Reykjavik participants
- description
- Exploring whether pre-diagnostic serum levels of 25(OH)D among older individuals living in Iceland were associated with survival after cancer diagnosis. We also assessed the risk of being diagnosed with cancer in association with 25(OH)D levels.
Primary outcomes (2)
- measure
- Overall survival
- timeFrame
- From date of diagnosis until death or censored at end of the follow-up (December 31, 2014)
- description
- The association between pre-diagnostic 25(OH)D levels in cancer patients and overall survival
- measure
- Cancer survival
- timeFrame
- From date of diagnosis until cancer death or censored at the end of the follow-up (December 31, 2014)
- description
- The association between pre-diagnostic 25(OH)D levels in cancer patients and cancer survival
Secondary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 66 Years
- Maximum age
- 98 Years
Show eligibility criteria text
Inclusion Criteria: * To participate in the AGES-Reykjavik study Exclusion Criteria: * To be diagnosed with cancer before study entry
References
Publications (1)
- BACKGROUNDHarris TB, Launer LJ, Eiriksdottir G, Kjartansson O, Jonsson PV, Sigurdsson G, Thorgeirsson G, Aspelund T, Garcia ME, Cotch MF, Hoffman HJ, Gudnason V. Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol. 2007 May 1;165(9):1076-87. doi: 10.1093/aje/kwk115. Epub 2007 Mar 10. PMID 17351290