Clinical trial · Interventional
Comparison of Three Tissue Acquiring Techniques During EUS Guided Biopsies of Solid Tumors.
Comparison of Three Different Tissue Acquisition Techniques During Endoscopic Ultrasound-guide Fine Needle Biopsies of Solid Tumors: A Randomized Single Blind Clinical Trial.
NCT03264092CI-TRIAL-00051005terminatedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Preliminary analysis of the results showed no statistically significant difference
Summary
Brief summary (as posted)
The study's aim is to prospectively compare three different tissue acquisition techniques during EUS guided solid lesions biopsies.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Solid Tumor | Solid Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endoscopic ultrasound guided fine needle biopsy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Wet suction
- description
- This arm will include all the patients that will get an endoscopic ultrasound guided fine needle biopsy done with the wet suction technique
- interventionNames
- Procedure: Endoscopic ultrasound guided fine needle biopsy
- type
- EXPERIMENTAL
- label
- Dry suction
- description
- This arm will include all the patients that will get and endoscopic ultrasound guided fine needle biopsy done with the dry suction technique
- interventionNames
- Procedure: Endoscopic ultrasound guided fine needle biopsy
- type
- EXPERIMENTAL
- label
- Slow pull
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Ages between 18-80 years old 2. Sex: male or female 3. Patients who require EUS and tissue sampling of solid solid lesions (size \>1 cm) anywhere in the following locations: lymph nodes, stomach, esophagus, colon, small intestine, pancreas, liver, spleen or kidney. 4. Patients who are able to give consent Exclusion Criteria: 1. Pregnant female 2. Coagulation disorders (platelets \< 50,000/mm3, INR \> 2) 3. Patients with acute pancreatitis in the immediate 2 weeks prior to the procedure. 4. Cardiorespiratory dysfunction that precludes sedation. 5. Unable to provide informed consent
References
Publications (3)
- BACKGROUNDYamao K, Sawaki A, Mizuno N, Shimizu Y, Yatabe Y, Koshikawa T. Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNAB): past, present, and future. J Gastroenterol. 2005 Nov;40(11):1013-23. doi: 10.1007/s00535-005-1717-6. PMID 16322944
- BACKGROUNDPuri R, Vilmann P, Saftoiu A, Skov BG, Linnemann D, Hassan H, Garcia ES, Gorunescu F. Randomized controlled trial of endoscopic ultrasound-guided fine-needle sampling with or without suction for better cytological diagnosis. Scand J Gastroenterol. 2009;44(4):499-504. doi: 10.1080/00365520802647392. PMID 19117242
- DERIVEDMendoza Ladd A, Casner N, Cherukuri SV, Garcia C, Padilla O, Dwivedi A, Hakim N. Fine Needle Biopsies of Solid Pancreatic Lesions: Tissue Acquisition Technique and Needle Design Do Not Impact Specimen Adequacy. Dig Dis Sci. 2022 Sep;67(9):4549-4556. doi: 10.1007/s10620-021-07316-4. Epub 2021 Dec 2. PMID 34859313