Clinical trial · Interventional
Percutaneous Ethanol Injection for Benign Cystic Thyroid Nodules
NCT03257930CI-TRIAL-00045112completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Use of ethanol injection in treatment of cystic thyroid nodule
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Thyroid Nodule | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ethanol injection | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- injection of ethanol
- description
- use of ethanol injection in the treatment of cystic thyroid nodule
- interventionNames
- Drug: ethanol injection
Primary outcomes (1)
- measure
- Reduction of volume of the cyst about 96.9%
- timeFrame
- Reduction of volume of the cyst about 96.9% within 6 month
- description
- Reduction of volume of the cyst about 96.9%
Secondary outcomes (1)
- measure
- symptomatic improvement
- timeFrame
- 3 month
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: 1. Adult male or female patient with cystic thyroid nodule 2. Presence of pressure symptoms or cosmetic problems 3. Benign lesions confirmed by histopathological examination by FNAC. 4. Serum levels of thyroid hormone thyrotropin, within normal limits. Exclusion Criteria: 1. Nodules showing malignant features(ie, speculated margin, markedly hypo echoic, micro- or macro calcifications) at US 2. solid thyroid nodule 3. mixed thyroid nodule(cystic with solid component)
References
Publications (2)
- BACKGROUNDVogel D, Durham AC, de Marcillac GD. Metastable aggregates in the polymerisation of tobacco-mosaic-virus protein. Eur J Biochem. 1977 Sep 15;79(1):161-71. doi: 10.1111/j.1432-1033.1977.tb11794.x. No abstract available. PMID 21087
- BACKGROUNDMonzani F, Lippi F, Goletti O, Del Guerra P, Caraccio N, Lippolis PV, Baschieri L, Pinchera A. Percutaneous aspiration and ethanol sclerotherapy for thyroid cysts. J Clin Endocrinol Metab. 1994 Mar;78(3):800-2. doi: 10.1210/jcem.78.3.8126160. PMID 8126160