Clinical trial · Interventional
Simulating Outcomes From Breast Conserving Surgery Using 3D Surface Imaging
The Use of 3D Surface Imaging to Simulate Outcome After Breast Conserving Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Most women with breast cancer are able to have an operation to remove the cancer while preserving the breast (breast conserving therapy, BCT). Whilst cancer control is the most important goal, appearance of the breast after surgery has been shown to affect the quality of a woman's life after treatment. This is even more relevant now that most women are surviving breast cancer. Before surgery, women are prepared for how they will look afterwards by having a discussion with the Surgeon or Breast Care Nurse. Sometimes women are shown two dimensional (2D) (standard) photographs of other women who had a similar operation. Patients have stated that viewing photographs of other patients does not prepare them adequately for their own experience of surgery. Three dimensional (3D) digital photography is currently being used to predict the appearance of the breasts after enlargement surgery using specialist software. The investigators intend to use a similar system to simulate a patient's appearance after BCT for cancer. The investigators believe that this will lead women to feel better prepared for their surgery, reduce stress, and lead to greater satisfaction with their breast after treatment. This study invites women undergoing BCT to be assigned at random to one of three groups receiving standard care (discussion), a 2D photograph, or the 3D simulation before their operation. The investigators will find out whether women feel better prepared for surgery and are more satisfied with their outcome if they are shown a simulated image of how their own breasts are likely to look. By taking 3D photographs of all study patients before and after surgery, a more accurate way to predict appearance after surgery will be developed for future patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer Female | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3-dimensional photograph with simulation | Other | — | UNRESOLVED |
| Viewing of a 2-dimensional photographic library | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- NO_INTERVENTION
- label
- Standard Care
- description
- Patient receives standard pre-operative preparation which involves a discussion in to the likely aesthetic outcome with their surgeon or specialist nurse
- type
- EXPERIMENTAL
- label
- 2-dimensional Portfolio
- description
- Patient views photographs of women matched for BMI, age, and breast volume who are 1-5 years post BCT pre-operatively.
- interventionNames
- Other: Viewing of a 2-dimensional photographic library
- type
- EXPERIMENTAL
- label
- 3-dimensional simulation
- description
- Patient pre-operatively views a simulation of their own breast of their likely outcome after BCT.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Female patients Over 18 years Planned for unilateral breast conserving surgery at RMH Planned to receive adjuvant whole breast radiotherapy at RMH Willing to attend for study follow up visits. Exclusion Criteria: * Previous or concurrent surgery to the contralateral breast (previous breast conserving surgery, breast reduction or mastectomy) * Previous surgery to the ipsilateral breast * Unable to stand for long enough to have clinical photos (approximately 5 minutes) * Unable to answer the BREAST-Q questionnaire (e.g. learning difficulties) * Visually impaired (so that they could not view a 2D/3D images) * Pre-operatively planning to have a symmetrisation procedure after radiotherapy.
References
Publications (1)
- DERIVEDGodden AR, Micha A, Wolf LM, Pitches C, Barry PA, Khan AA, Krupa KDC, Kirby AM, Rusby JE. Three-dimensional simulation of aesthetic outcome from breast-conserving surgery compared with viewing photographs or standard care: randomized clinical trial. Br J Surg. 2021 Oct 23;108(10):1181-1188. doi: 10.1093/bjs/znab217. PMID 34370833