Clinical trial · Observational
Surveillance of Patients With Precancerous Lesions of the Stomach
Surveillance Strategies of Patients With Precancerous Conditions and Lesions in the Stomach
NCT03250091CI-TRIAL-00034471recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The project will aim to identify and determine subgroups of patients with different risks of progression to gastric cancer and to assess appropriate follow-up intervals. Implementing risk stratification only high risk individuals will be offered and performed endoscopic surveillance.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Atrophy | — | UNRESOLVED | — |
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
| Gastric Dysplasia | — | UNRESOLVED | — |
| Gastric Intestinal Metaplasia | — | UNRESOLVED | — |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biopsies for gastric microbiota | Procedure | — | UNRESOLVED |
| Faecal sample acquisition | Procedure | — | UNRESOLVED |
| Plasma/serum sampling | Procedure | — | UNRESOLVED |
| Upper endoscopy with biopsies | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (7)
- label
- Gastric cancer
- description
- Gastric adenocarcinoma and other gastric malignancies
- interventionNames
- Procedure: Upper endoscopy with biopsies
- Procedure: Plasma/serum sampling
- Procedure: Biopsies for gastric microbiota
- Procedure: Faecal sample acquisition
- label
- Gastric mucosal dysplasia
- description
- Includes: a. High-grade dysplasia; b. Low-grade dysplasia; c. Indefinite for dysplasia
- interventionNames
- Procedure: Upper endoscopy with biopsies
- Procedure: Plasma/serum sampling
- Procedure: Biopsies for gastric microbiota
- Procedure: Faecal sample acquisition
- label
- High-risk IM gastritis stages
- description
- High-risk stages according to OLGIM classification: OLGIM Stage IV and OLGIM Stage III.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: Patients undergoing upper endoscopy Motivation to participate in the study Signed consent Exclusion Criteria: Known gastric cancer Unwillingness or inability to co-operate
References
Publications (1)
- BACKGROUNDDinis-Ribeiro M, Areia M, de Vries AC, Marcos-Pinto R, Monteiro-Soares M, O'Connor A, Pereira C, Pimentel-Nunes P, Correia R, Ensari A, Dumonceau JM, Machado JC, Macedo G, Malfertheiner P, Matysiak-Budnik T, Megraud F, Miki K, O'Morain C, Peek RM, Ponchon T, Ristimaki A, Rembacken B, Carneiro F, Kuipers EJ; European Society of Gastrointestinal Endoscopy; European Helicobacter Study Group; European Society of Pathology; Sociedade Portuguesa de Endoscopia Digestiva. Management of precancerous conditions and lesions in the stomach (MAPS): guideline from the European Society of Gastrointestinal Endoscopy (ESGE), European Helicobacter Study Group (EHSG), European Society of Pathology (ESP), and the Sociedade Portuguesa de Endoscopia Digestiva (SPED). Endoscopy. 2012 Jan;44(1):74-94. doi: 10.1055/s-0031-1291491. Epub 2011 Dec 23. PMID 22198778