Clinical trial · Interventional
Pharmacokinetics and Metabolism Study in Healthy Male Participants
Pharmacokinetics and Metabolism of [14C] BMS-986205 in Healthy Male Participants
NCT03247283CI-TRIAL-00030172completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Phase 1 Phamacokinetic and metabolism study of BMS-986205 in healthy males
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| BMS-986205 | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Single Oral Dose of BMS-986205
- interventionNames
- Drug: BMS-986205
Primary outcomes (6)
- measure
- Area Under the Concentration-Time Curve from Time Zero to Time of Last Quantifiable Concentration (AUC[0-T])
- timeFrame
- up to 28 days
- description
- Measured by plasma concentrations
- measure
- Percent of Total Radioactivity Recovered in All Excreta (% total)
- timeFrame
- up to 28 days
- description
- Measured by plasma urine, feces, and vomit (if applicable) volumes and radioactivity counts
- measure
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 18 Years
- Maximum age
- 50 Years
Show eligibility criteria text
Inclusion Criteria: * Body weight 75-95kg, BMI 18.0-32.0 kg/m\^2 * Refrain from sperm donation 110 days after dosing Exclusion Criteria: * Current or recent gastrointestinal disease * Any GI surgery that could impact drug absorption * Active, known, or suspected autoimmune disease Other protocol defined inclusion/exclusion criteria could apply
References
Publications (0)
Data not yet available
No reference posted for this study.