Clinical trial · Interventional
Multimodal Analgesia in Laparoscopic Radical Gastrectomy With Gastric Cancer: a Multi-center Study
NCT03236051CI-TRIAL-00028875unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The study is aimed to explore the effects of multimodal analgesia consisting of ropivacaine's wound infiltration, parecoxib's intravenous injection and oxycodone-acetaminophen tablets' oral administration on postoperative pain and rehabilitation after laparoscopic radical gastrectomy for patients with gastric cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Gastric Cancer | Malignant Gastric Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multimodal analgesia | Procedure | — | UNRESOLVED |
| PCIA analgesia | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- multimodal analgesia
- description
- Patients received multimodal analgesia after laparoscopic gastrectomy .
- interventionNames
- Procedure: Multimodal analgesia
- type
- ACTIVE_COMPARATOR
- label
- PCIA analgesia
- description
- Patients received PCIA analgesia after laparoscopic gastrectomy.
- interventionNames
- Procedure: PCIA analgesia
Primary outcomes (1)
- measure
- Numeric rating scales (NRS) score with 24 hours after the surgery
- timeFrame
- 1 day
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 75 Years
Show eligibility criteria text
Inclusion Criteria: 1. Requirements of informed consent and assent of participant, parent or legal guardian as applicable. 2. Patients underwent laparoscopic radical gastrectomy under general anesthesia and between the age of 18 and 75 years old without considering sex. 3. American Society of Anesthesiologists (ASA) physical status I-III. 4. Participants can follow the drug doses and visit plan Exclusion Criteria: 1. Patients certified by a doctor that doesn't fit to participate in this study. 2. Patients allergic to opioids, sulfas, parecoxib, non-steroidal drugs, acetaminophen, tramadol etc.. 3. Patients with ischemic heart disease, cerebrovascular disease and peripheral vascular disease, or their cardiac function \> II (NYHA) patients, patients received coronary artery bypass grafting (CABG) recently, and patients with severe hypertension (systolic pressure≥180mmHg or diastolic pressure≥110mmHg). 4. Patients with gastric cancer with distant metastasis. 5. Patients with severe infection, respiratory dysfunction, coagulation disorders, severe liver and renal dysfunction (Child - Pugh≥ 10; creatinine clearance \< 25 ml/min). 6. Patients with suspect or have a history of drug abuse. 7. Pregnancy and lactation women, or have a pregnancy plan within a month after the test of the subjects (also including male participants). 8. Sponsors or researchers directly involved in the testing or their family members. 9. Patients with conversion, palliative resection. 10. Patients with chronic pain（NRS≥3）or using opioids or NSAIDs before surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.