Clinical trial · Observational
Hepatocellular Carcinoma Registry in Asia: The INSIGHT Registry
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The INSIGHT ('Insight into Real-world Practice of Management of HCC in Asia-Pacific') registry is designed as a multi-centre longitudinal cohort study of patients diagnosed with HCC between 1st January 2013 and 31st December 2019 in nine countries (i.e., South Korea, Taiwan, Thailand, Japan, China, Hong Kong, Australia, New Zealand and Singapore). Approximately 30% of the sample size will be identified retrospectively and 70% will be identified prospectively from the start date of the registry (October 2016), with an even distribution of consecutively diagnosed patients within the different years.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Hepatocellular Carcinoma | Hepatocellular Carcinoma | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (10)
- measure
- Overall Survival
- timeFrame
- From diagnosis or treatment initiation to date of death due to any cause, or last known vital status date, up to 2 years
- measure
- Progression-free survival
- timeFrame
- From treatment initiation for advanced or metastatic HCC to the first date of disease progression or death due to any cause, whichever occurred first, up to 2 years
- description
- Patients lost for follow up or withdrawn from the study will be censored at the last disease assessment date
- measure
- Time to progression
- timeFrame
- From the start of treatment for a disease until disease progression, up to 2 years
- description
- Measuring the time to progression is one way to see how well a new treatment works. Also called TTP.
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 21 Years
- Maximum age
- 99 Years
Show eligibility criteria text
Inclusion Criteria: * Female or male aged 21 or above. * Patient with confirmed diagnosis of HCC between 1st January 2013 and 31st December 2019 based on one or more of the following criteria: * American Association for the Study of Liver Diseases (AASLD) criteria * Asian Pacific Association for the Study of the Liver (APASL) criteria * Histology/cytology * Space occupying lesion in the liver and an serum alpha-feto protein of \> 400 ng/mL in a patient with chronic viral hepatitis or cirrhosis from any cause * Informed consent form (ICF) to be presented and signed by patients who are still alive at the point of study enrolment, per local regulations. For the collection of data for deceased subjects, appropriate waiver of consent as per local regulations and guidelines will have to be in place. * Patient who is being followed-up at the participating site. Exclusion Criteria: \- Patients participating in any HCC-related therapeutic/interventional clinical trial.
References
Publications (0)
Data not yet available