Clinical trial · Interventional
Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma)
Impact of Lymph Node Dissection in the Management of High-risk Primary Upper Tract Urothelial Carcinoma Patients
NCT03230201CI-TRIAL-00028973UTUCunknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This clinical trial is designed to evaluate the role of lymph node dissection in the prevention of recurrence and metastasis after radical nephroureterectomy for high-risk primary upper tract urothelial carcinoma (UTUC) patients.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lymph Node Dissection | — | UNRESOLVED | — |
| Metastasis | — | UNRESOLVED | — |
| Recurrence | — | UNRESOLVED | — |
| Upper Tract Urothelial Carcinoma | Renal Pelvis and Ureter Carcinoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Lymph node dissection | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- NO_INTERVENTION
- label
- Blank control
- description
- do not receive Lymph node dissection during surgery.
- type
- EXPERIMENTAL
- label
- Lymph node dissection
- description
- will receive Lymph node dissection during radical nephroureterectomy.
- interventionNames
- Procedure: Lymph node dissection
Primary outcomes (1)
- measure
- overall survival
- timeFrame
- three years after surgery
Secondary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * I. Suspected high-risk UTUC patients without metastases in their preoperative radiological imaging (cN0M0).II. Suspected high-risk UTUC patients without history of bladder tumor. III. Suspected high-risk UTUC patients without synchronous bladder tumor. IV. Suspected high-risk UTUC patients without contralateral UTUCs Exclusion Criteria: * I. Patients with significant metastases in their preoperative radiological imaging. II. Patients with history of bladder tumor. III. Patients with synchronous bladder tumor. IV. Patients with contralateral UTUCs. V. Patients with advanced stage (T4). VI. Patients with other malignant tumors
References
Publications (0)
Data not yet available
No reference posted for this study.