Clinical trial · Interventional
Superior Hypogastric Plexus Block Versus Pulsed Radiofrequency for Chronic Pelvic Cancer Pain
Superior Hypogastric Plexus Block and Pulsed Radiofrequency on Dorsal Root Ganglia of Sacral Nerves for Chronic Pelvic Cancer Pain
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Cancer-related pain represents a major challenge for both clinicians and patients. This pain can be associated directly with the cancer or with certain treatments administered to the patient. 52.1% of cancer patients suffer from pain and that 62.6% are not satisfied with the current pain treatment. Pain prevalence is high in developing countries due to late diagnosis and major impediments to opioid access
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Pelvic Cancer Pain | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pulsed radiofrequency | Radiation | — | UNRESOLVED |
| superior hypogastric plexus block | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- the study group one
- description
- 20 patients with superior hypogastric plexus block
- interventionNames
- Procedure: superior hypogastric plexus block
- type
- EXPERIMENTAL
- label
- the study group two
- description
- 20 patients with superior hypogastric plexus block combined to pulsed radiofrequency on sacral nerve roots 2,3 and 4
- interventionNames
- Procedure: superior hypogastric plexus block
- Radiation: pulsed radiofrequency
Primary outcomes (1)
- measure
- Visual analogue score for pain
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * sympathetically maintained pelvic, perineal pain * pain is no longer controlled with oral morphine sustained release tablets 30 mg * excessive sedation or other side effects from oral morphine sustained release tablets 30 mg or amitryptyline tablets 25 mg * age between 18-70 years Exclusion Criteria: * patient refusal * patients with coagulopathies * allergy to constant dyes or phenol * patients receiving radiation or chemotherapy within 4 weeks of neurolytic block * patients with major or moderate cardiac/respiratory incapacitating diseases * liver and renal failure * patients younger than 18 years and older than 70 years
References
Publications (2)
- BACKGROUNDSindt JE, Brogan SE. Interventional Treatments of Cancer Pain. Anesthesiol Clin. 2016 Jun;34(2):317-39. doi: 10.1016/j.anclin.2016.01.004. PMID 27208713
- DERIVEDHetta DF, Mohamed AA, Abdel Eman RM, Abd El Aal FA, Helal ME. Pulsed Radiofrequency of the Sacral Roots Improves the Success Rate of Superior Hypogastric Plexus Neurolysis in Controlling Pelvic and Perineal Cancer Pain. Pain Physician. 2020 Mar;23(2):149-157. PMID 32214294