Clinical trial · Interventional
Postoperative Pain After Single Port, Two Ports and Three Ports VATS Lobectomy
Postoperative Pain After Single Port, Two Ports and Three Ports Video-assisted Thoracic Surgery Lobectomy in Cancer Patients: A Randomized Controlled Trial
NCT03228056CI-TRIAL-00032460unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This single-center, prospective, randomized controlled trial was designed to assess and compare the postoperative pain after VATS lobectomy performed though one, two and three incisions. The primary outcome measure is pain intensity measured in VAS scale. The secondary outcome measure is cumulative morphine consumption up to 72 hours after surgery
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| pain intensity measured in VAS scale | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- uniportal VATS lobectomy
- description
- * uniportal VATS lobectomy * thoracic epidural block (0.125% bupivacaine with epinephrine 1:50000, continuous infusion 3-4 ml/hour) * ketoprofene 100 mg i.v every 12 hours * paracetamol 1000 mg i.v every 8 hours * rescue doses of morphine in PCA system (bolus dose 2 mg i.v) * pain intensity measured in VAS scale
- interventionNames
- Diagnostic Test: pain intensity measured in VAS scale
- type
- ACTIVE_COMPARATOR
- label
- two-ports VATS lobectomy
- description
- * two-ports VATS lobectomy * thoracic epidural block (0.125% bupivacaine with epinephrine 1:50000, continuous infusion 3-4 ml/hour) * ketoprofene 100 mg i.v every 12 hours * paracetamol 1000 mg i.v every 8 hours * rescue doses of morphine in PCA system (bolus dose 2 mg i.v) * pain intensity measured in VAS scale
- interventionNames
- Diagnostic Test: pain intensity measured in VAS scale
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. American Society of Anesthesiologists (ASA) physical status 1-3 2. undergo videothoracoscopic lung lobectomy 3. forced expiratory volume in 1 second (FEV1) \>1,5 l/min 4. no contraindications for epidural anesthesia 5. ability to comprehend principles of VAS pain examination method and to communicate in accordance with them. Exclusion Criteria: 1. prior to the study: contraindications for local anesthesia, ASA\>3, FEV1\<1,5 l/min, conditions disabling the patient from comprehending the principles of VAS pain examination, known allergy to used medications. 2. during the study: failure to place epidural catheter, decision to abandon lobar resection (e.g. in case of neoplastic dissemination), intraoperative conversion to thoracotomy, intraoperative anatomical obstacles to distribution of local anesthetics, conditions disabling the patient from pain evaluation by means of VAS method (e.g. postoperative delirium), necessity to administer other pharmaceuticals influencing pain perception (e.g. sedatives), necessity of mechanical ventilation, interruption of local anesthesia as a result of technical problems (e.g. damage or slippage of catheter).
References
Publications (0)
Data not yet available
No reference posted for this study.