Clinical trial · Interventional
Assessment of High Flow Nasal Cannula Oxygenation in EBUS Bronchoscopy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study is a prospective randomised trial where a computer will randomly allocate patients to one of two possible methods of delivering oxygen during the procedure of bronchoscopy. This trial compares high flow nasal cannula (HFNC) with nasal prongs in delivering oxygen to patients undergoing endo-bronchial ultrasound guided trans- bronchial nodal aspiration (EBUS-TBNA) a specialised form of bronchoscopy procedure. HFNC uses humidified higher gas flow rates than conventional low flow systems such as nasal prongs which are limited by the respiratory rate and effort.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
| Lymphadenopathy | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| high flow nasal oxygen | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- High flow nasal oxygen
- description
- (Optiflow; Fisher \& Paykel, Auckland, New Zealand)
- interventionNames
- Device: high flow nasal oxygen
- type
- ACTIVE_COMPARATOR
- label
- Nasal prongs
- interventionNames
- Device: high flow nasal oxygen
Primary outcomes (1)
- measure
- drop in oxygen saturation during procedure
- timeFrame
- through procedure completion defined as withdrawing scope from patient's mouth, an average of 30 minutes
- description
- the difference in oxygen saturation levels between pre-treatment assessments and the lowest saturation level achieved during treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Subjects with a peripheral arterial pulse oximetry ≥ 90% breathing room air * Age ≥ 18 years * Able to breathe spontaneously throughout the procedure Exclusion Criteria: * Respiratory or cardiac failure * Recent myocardial infarction \< 6 weeks ago * On long term oxygen therapy, those with tracheostomy and/ or non-invasive or invasive mechanical ventilation * Nasal and/ or nasopharyngeal disease * Inability to give informed consent * Dementia * Hepatic or end stage renal disease * Pregnancy
References
Publications (0)
Data not yet available