Clinical trial · Interventional
Home Respiratory Rehabilitation in Advanced Lung Cancer Chemotherapy Per os
Home Respiratory Rehabilitation in Patients With Lung Cancer Non-small Cell Advanced or Metastatic Treated With Oral Targeted Therapy
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The feasibility and impact of respiratory rehabilitation (RR) in patients with advanced or metastatic (EGF-R WT or mutated) non-small cell lung cancer treated with oral targeted therapy including Inhibitors of EGF-R tyrosine kinases (TKI) and ALK inhibitors. These patients will benefit, at the beginning of the chemotherapy whatever the treatment line, of a respiratory rehabilitation. The respiratory rehabilitation takes place at the patient's home with the HAD's cooperation 3 hours per week, divided into 2 or 3 sessions. There is associated educational, nutritional and psychological support for a total duration of 8 weeks.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Respiratory rehabilitation | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- 8 weeks Respiratory rehabilitation
- interventionNames
- Other: Respiratory rehabilitation
Primary outcomes (1)
- measure
- Rate of patients completing the full Respiratory Rehabilitation (8 weeks) at home
- timeFrame
- At 8 weeks
Secondary outcomes (7)
- measure
- Functional Assessment of Cancer Therapy Lung standardized
- timeFrame
- Baseline and 8 weeks
- description
- measure the quality of life
- measure
- EORTC QLQ C-30 standardized version 3.0
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient with advanced or metastatic lung cancer * In the course of treatment by oral chemotherapy of oral targeted therapy (tyrosine kinase inhibitor) in 1st, 2nd, 3rd line or more at the time of their inclusion * Diagnosis of CP retained after multidisciplinary discussion of patient records Exclusion Criteria: * Any residual toxicity of a previous antineoplastic treatment, grade\> 2. * Cardio-respiratory contraindications to exercise re-training: * Angina unstable * Recent infarct * Tight aortic stenosis * Unsteady heart failure * Pericarditis, endocarditis, myocarditis * Evolutionary thromboembolic disease * Ventricular aneurysm * Intra ventricular thrombus * Uncontrolled rhythm disorders * Instability of the respiratory state defined by uncompensated respiratory acidosis * Carcinological contraindications: * Bone metastases at risk of fracture and / or algae despite optimal analgesic treatment, symptomatic central nervous system metastases * Presence of anemia (Hb \<8g / dl or \<10g / dl if patient with previous cardiac history), thrombocytopenia (\<100,000 platelets / mm3) * Chimio toxicity (neurological, cardiac) according to the investigator's assessment * Neuromuscular contraindications: * Neuromuscular and / or osteo-articular disease making it impossible to re-train * Severe cognitive impairment * Patient under tutorship or curatorship
References
Publications (0)
Data not yet available