Clinical trial · Interventional
CDx Biopsies for Detection of Laryngopharyngeal Reflux and Laryngeal Lesions
NCT03214835CI-TRIAL-00046031withdrawnN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Study halted prematurely, prior to enrollment of first participant.
Summary
Brief summary (as posted)
The study will take place at Rambam medical center, department of Otolaryngology Head and Neck Surgery, for two years. Patients suspected of LPR or laryngeal l tumor and are candidate for laryngeal or hypopharyngeal biopsies will be recruited.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Laryngeal Disease | — | UNRESOLVED | — |
| Laryngeal Tumor | — | UNRESOLVED | — |
| Laryngopharyngeal Reflux | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Endo CDx Brush biopsy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Brush biopsy for laryngeal lesion
- description
- Brush biopsy of the larynx - in addition to the standard biopsy
- interventionNames
- Device: Endo CDx Brush biopsy
- type
- EXPERIMENTAL
- label
- Brush biopsy for LPR
- description
- Brush biopsy of the larynx at the post cricoid region - in addition to the standard examination for LPR (PH monitoring double probe)
- interventionNames
- Device: Endo CDx Brush biopsy
Primary outcomes (1)
- measure
- Efficacy of EndoCDx brush
- timeFrame
- 3 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age 18 or over * patients suspected to suffer from LPR * Patients with laryngeal/hypopharyngeal lesions. Exclusion Criteria: * Patient refusal * Patients with anatomical variants which precludes biopsy taking. * Patients with allergy to lidocain-based local anesthesia agents.
References
Publications (0)
Data not yet available
No reference posted for this study.