Clinical trial · Interventional
Study of Intraoperative Radiotherapy for Middle and Low Rectal Cancer
Single Center Study of Intraoperative Radiotherapy for Middle and Low Rectal Cancer in the Standard of Peritoneal Inversion Rectal Cancer.
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To study the application of Intersphincteric Resection（ISR）combined with intraoperative radiation therapy(IORT) for ultra-low rectal cancer,and to broaden the surgical indications of Intersphincteric Resection（ISR. The study is aimed to assess the postoperative acute complication and the short-term acute efficacy on the patients with middle and low rectal cancer by treated with intraoperative radiotherapy,especially those with peritoneal inversion rectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Intraoperative radiotherapy by Intrabeam（Zeiss Meditech，Jena，Germany） | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- A group
- description
- Colorectal cancer patients first are given antineoplastic drugs and then transfer to operative room to be treated by surgical resection and the radiotherapy is given during the operation after the removal of the tumour.
- interventionNames
- Radiation: Intraoperative radiotherapy by Intrabeam（Zeiss Meditech，Jena，Germany）
- type
- NO_INTERVENTION
- label
- B group
- description
- Colorectal cancer patients first are given antineoplastic drugs and then transfer to operative room to be treated only by surgical resection and no radiotherapy afer the removal of the tumour.
Primary outcomes (2)
- measure
- Decide and record the region of radiotherapy
- timeFrame
- Intraoperation
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 40 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: Inclusion Criteria: * Aged 40 to 80 years old, gender not limited. * Be diagnosed as colorectal cancer by coloscopy. * Patients with middle and low rectal cancer,whose preoperative staging evaluation is T3 ,T4 or N+. * Accept surgery and intraoperative radiotherapy. * Signed informed consent Exclusion Criteria: * the patients whose preoperative evaluation is below T3 stage with middle and rectal cancer. * Active internal bleeding (such as gastrointestinal bleeding), urogenital system, or have not cure of peptic ulcer in four weeks * Severe liver and kidney dysfunction * Intracranial tumor, suspicious aortic dissection, arteriovenous malformation, aneurysm * Thrombolysis treatment in one week * Allergies of thrombolysis drug or contrast * Participated in any clinical trials within three months
References
Publications (0)
Data not yet available