Clinical trial · Observational
Cancer Care Delivery in Adolescent and Young Adult Patients With Acute Lymphoblastic Leukemia
Documentation and Delivery of Guideline-Consistent Treatment in Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL)
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study investigates cancer care delivery in adolescent and young adult patients with acute lymphoblastic leukemia. Surveying institutions, evaluating delivery of care at the patient level and seeking input from healthcare providers may help doctors increase rates of adherence to National Comprehensive Cancer Network (NCCN) treatment guidelines. It may also improve care for adolescent and young adult patients with acute lymphoblastic leukemia.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Discussion | Behavioral | — | UNRESOLVED |
| Medical Chart Review | Other | — | UNRESOLVED |
| Questionnaire Administration | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Observational (cancer care delivery analysis)
- description
- CHART REVIEW: Patient medical record data is abstracted and treatment plans are reviewed for consistency to NCCN guidelines. For each patient, induction and post-induction care is recorded as either concordant with NCCN guidelines or non-concordant with NCCN guidelines. SITE QUESTIONNAIRE: Participating sites complete a questionnaire which is designed to capture facility-oriented data. FOCUS GROUPS: Healthcare providers participate in focus groups over 2-3 hours to discuss facilitators and barriers to AYA ALL guideline concordance. Participants provide responses which will be recorded on a flip-chart or white board, followed by discussion of the ideas for clarification
- interventionNames
- Behavioral: Discussion
- Other: Medical Chart Review
- Other: Questionnaire Administration
Primary outcomes (7)
- measure
- Proportion of patients with a documented treatment plan concordant with National Comprehensive Cancer Network (NCCN) guidelines for adolescent and young adults with acute lymphoblastic leukemia
- timeFrame
- Overall evaluation window, an average of 12 weeks after start of treatment
- description
- Primary analysis will describe the proportion of patients meeting this endpoint in overall evaluation window.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 15 Years
- Maximum age
- 39 Years
Show eligibility criteria text
Inclusion Criteria: * Newly diagnosed with either Ph- or Ph+ ALL between January 1st, 2012 and December 31st, 2016 * Age at diagnosis: 15-39 years, inclusive * Both diagnosed and initially treated at the participating National Cancer Institute Community Oncology Research Program (NCORP) institution during induction and post-induction therapy (PIT) * Aim 3: Healthcare professional currently employed at a participating NCORP institution * Eligible healthcare providers include but are not limited to: physicians, registered nurses (RNs), nurse practitioners, physician assistants, patient advocates, social workers, pharmacists and clinical research associates (CRAs) * Aim 3: Direct involvement in the care of AYA ALL patients Exclusion Criteria: * Diagnosis of secondary ALL * Diagnosis of mixed lineage acute leukemia * Diagnosis of acute leukemia of ambiguous lineage (ALAL) * Diagnosis of Burkitt's leukemia * Transfer of care to another institution during induction or post-induction therapy (PIT) * Aim 3: Trainee
References
Publications (0)
Data not yet available