Clinical trial · Interventional
Inflammatory Stress Response in Pediatric Inguinal Hernia Repair
Comparison of Inflammatory Stress Response Between Laparoscopic and Open Approach for Pediatric Inguinal Hernia Repair
NCT03203343CI-TRIAL-00036163completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access. Investigators would compare both groups to find out witch one does the lesser inflammatory stress response on the organism.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Children, Only | — | UNRESOLVED | — |
| C Reactive Protein | — | UNRESOLVED | — |
| Inflammatory Response | — | UNRESOLVED | — |
| Inguinal Hernia, Indirect | — | UNRESOLVED | — |
| Interleukin-6 | — | UNRESOLVED | — |
| Surgery | — | UNRESOLVED | — |
| Tumor Necrosis Factor Alpha | — | UNRESOLVED | — |
| White Blood Cell Count, Leukocytes | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Operation - MARCY | Procedure | — | UNRESOLVED |
| Operation - PIRS | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- PIRS group
- description
- Patients operated laparoscopically - PIRS technique
- interventionNames
- Procedure: Operation - PIRS
- type
- ACTIVE_COMPARATOR
- label
- Marcy group
- description
- Patients operated by open modified Marcy technique
- interventionNames
- Procedure: Operation - MARCY
Primary outcomes (4)
- measure
- Change in inflammatory stress response (IL6)
- timeFrame
- 3 measurements: preoperative, 24 hours after and 6 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- Male
- Minimum age
- 3 Years
- Maximum age
- 7 Years
Show eligibility criteria text
Inclusion Criteria: * male children with inguinal hernia at age of 3 to 7 * one-sided inguinal hernia Exclusion Criteria: * Female children * recurrent hernia * bilateral hernia * age less than 3 y, more than 7 y * any general inflammatory process, illness * intraoperative complications which may interfere with inflammatory stress response
References
Publications (1)
- DERIVEDJukic M, Pogorelic Z, Supe-Domic D, Jeroncic A. Comparison of inflammatory stress response between laparoscopic and open approach for pediatric inguinal hernia repair in children. Surg Endosc. 2019 Oct;33(10):3243-3250. doi: 10.1007/s00464-018-06611-y. Epub 2018 Dec 3. PMID 30511312