Clinical trial · Interventional
Comparison of Energy Instruments and Stapling Device to Dissect Intersegmental Plane in Segmentectomy
Comparison of Energy Instruments and Stapling Device to Dissect Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): One treatment policy showed an advantage at a very high significance level.
Summary
Brief summary (as posted)
According to published studies, there are two main approaches in the dissection of intersegmental plane: stapling devices and energy instrument separation. However, only a few retrospective studies focused on the perioperative outcomes of these two approaches, and there has been no definitive conclusion about which method is better. So the investigators want to conduct a prospective study, trying to figure out this problem.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Segmentectomy | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Energy Instruments | Device | — | UNRESOLVED |
| Stapling Device | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Energy Instruments Group
- description
- All enrolled patients will accept robot-assisted or uniportal segmentectomy. After cutting off the relevant segmental arteries and veins, we clamp the segmental bronchus, and then the diseased lung will be ventilated to identify the border of segment according to the collapse region. We use energy instruments dissect intersegmental plane along the determined border. If fast-frozen pathology confirms lung cancer, we will do lymphadenectomy. At last, a drainage tube will be placed.
- interventionNames
- Device: Energy Instruments
- type
- EXPERIMENTAL
- label
- Stapling Device Group
- description
- All enrolled patients will accept robot-assisted or uniportal segmentectomy. After cutting off the relevant segmental arteries and veins, we clamp the segmental bronchus, and then the diseased lung will be ventilated to identify the border of segment according to the collapse region. We use stapling device to dissect intersegmental plane along the determined border. If fast-frozen pathology confirms lung cancer, we will do lymphadenectomy. At last, a drainage tube will be placed.
- interventionNames
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * 1\. Age: 18 to 70 years old; 2. Pulmonary nodules or GGO found in chest CT examination, and conform with indications for segmentectomy mentioned in NCCN guidelines: 1. Poor pulmonary reserve or other major comorbidity that contraindicates lobectomy; 2. Peripheral nodule ≤2 cm with at least one of the following: <!-- --> 1. Pure (Adenocarcinoma in situ) AIS histology; 2. Nodule has ≥50% ground-glass appearance on CT; 3. Radiologic surveillance confirms a long doubling time (≥400 days). 3. Normal in preoperative tests, such as blood routine examination, liver function, renal function, coagulation function, etc. 4\. ASA score: Grade I-III. 5. Patients who can coordinate the treatment and research and sign the informed consent. Exclusion Criteria: * 1\. Patients have history of malignant tumor, or have accepted neoadjuvant chemotherapy and(or) radiotherapy. 2\. Patients have comorbidities in cardiovascular, kidney, lung or hematopoietic system, who cannot tolerate the surgery. 3\. Psychiatric patients。 4. Patient have history of chest trauma or surgery on ipsilateral chest.
References
Publications (0)
Data not yet available