Clinical trial · Interventional
Anti-inflammatory Cells in Peritoneal Cavity
Can the Peritoneal Cavity be a Source of Regulatory B Cells to Treat Auto-immune Disease?
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Absence of BReg Lymphocytes in peritoneum
Summary
Brief summary (as posted)
Some subsets of lymphocytes are able to inhibit immune response and thus, could be used to control auto-immune diseases and transplant reject. In mice, the main source of those anti-inflammatory lymphocytes is the peritoneal cavity. No data are available in human. This study aims at exploring the presence of those anti-inflammatory lymphocytes in human peritoneal cavity and at determine how to expand those cells.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chronic Renal Insufficiency | — | UNRESOLVED | — |
| Ovarian Cysts | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| peritoneal fluid and blood sample | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- OTHER
- label
- subjects with ovarian cyst
- description
- Peritoneal fluid sample obtained from coelioscopy for exploration of ovarian cysts and blood sample
- interventionNames
- Other: peritoneal fluid and blood sample
- type
- OTHER
- label
- subjects with peritoneal dialysis
- description
- Peritoneal fluid sample obtained from peritoneal dialysis fluid of patients with chronic renal insufficiency and blood sample
- interventionNames
- Other: peritoneal fluid and blood sample
Primary outcomes (1)
- measure
- relative percentage of regulatory B cells among B cells in peritoneal cavity compared to peripheral blood
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion criteria: * woman over 18 year old undergoing exploration of ovarian cysts by coelioscopy * patient with chronic renal insufficiency undergoing peritoneal dialysis * informed consent obtained Exclusion criteria: * pregnancy or breast-feeding * non affiliation to health care insurance * treatment with corticosteroids over 15 mg/day * treatment with rituximab
References
Publications (0)
Data not yet available