Clinical trial · Observational
Collection of Malignant Ascites, Pleural Fluid, and Blood From People With Solid Tumors
Collection of Malignant Ascites, Pleural Fluid and Blood From Patients With Solid Tumors
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): PI left NIH
Summary
Brief summary (as posted)
Background: Researchers want to study fluids and blood of people with cancer. The fluids are from the abdomen and around the lungs. Studying these might help researchers learn about the biology of cancer. This may lead to better ways to treat cancer. Objectives: To study the biology of cancer. Eligibility: Adults 18 and older with malignant solid tumors. Design: Participants will be screened with medical history, blood tests, and confirmation of diagnosis. Participants will have samples taken at regularly scheduled procedures. Fluids from the abdomen and/or lungs will be taken as part of the procedures. Blood will be taken separately. Participants may be asked to give more samples at future procedures.
Conditions
Conditions (4)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer | Malignant Neoplasm | ALIAS | 0.90 |
| Fallopian Tube Cancer | Malignant Fallopian Tube Neoplasm | ALIAS | 0.90 |
| Ovarian Cancer | Malignant Ovarian Neoplasm | CURATED_EXACT | 0.92 |
| Primary Peritoneal Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (1)
- label
- Cohort 1
- description
- Patients with a diagnosis of malignant solid tumor
Primary outcomes (1)
- measure
- To obtain blood samples, ascites and pleural effusion samples from patients with solid tumor malignancies, with the intent of performing translational studies related to cancer.
- timeFrame
- Ongoing
- description
- Experimental - Translational study outcomes from the collection/analysis of blood samples; and ascites and pleural effusion samples from patients with solid tumor malignancies.
Secondary outcomes (6)
- measure
- Develop the malignant fluid as a culture model to replicate intraperitoneal growth of ovarian cancers.
- timeFrame
- ongoing
- measure
- Characterize malignant effusion composition through immunohistochemistry and flow cytometry.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
* INCLUSION CRITERIA: * Participants greater than or equal to 18 years of age with histologically proven malignant solid tumors * Ability and willingness to provide informed consent to participation. * Participants with malignant solid tumors with a clinical indication for a thoracentesis or paracentesis. EXCLUSION CRITERIA: -Children \< 18 years of age are not eligible.
References
Publications (0)
Data not yet available