Clinical trial · Observational
National Breast and Thyroid Screening After a Treatment Received Against a Cancer During Childhood
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The DENACAPST programme represents an important initiative to provide near nation-wide roll-out of an important cancer surveillance program for childhood cancer survivors. The program is based on internationally recognized standards in cancer surveillance, which were developed by the International Guideline Harmonization Group (IGHG) with support of all relevant stakeholders in cancer survivorship research and clinical work in Europe, Canada and the United States and recognized French recommendations about breast screening for women at high risk of cancer. With this programme, French centers organized themselves to provide to childhood cancer survivors adequate medical attention, which includes close medical surveillance for breast/thyroid cancer where appropriate, based on adequate risk stratification. The aim of the study is to analyze if the recommendations about breast and thyroid cancer screening are followed in this population and secondly to provide more informations about these second cancers and about the screening.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early Detection of Cancer | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- follow of cancer screening recommendations
- timeFrame
- 2 years
- description
- number of persons at risk found percentage of persons at risk contacted who answered percentage of persons contacted, who answered, who accepted the screening
Secondary outcomes (4)
- measure
- description of thyroid cancer screening
- timeFrame
- 2 years
- description
- evaluation of the programme
- measure
- description of breast cancer screening
- timeFrame
- 2 years
- description
- evaluation of the programme
- measure
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * childhood cancer survivor, and * treated with radiotherapy * health status compatible, and * have had a long-term follow-up consultation describing a personalized post-cancer plan and, * informed consent signed by patient \+ Inclusion criteria for breast screening * being a woman and being 25 years or more for breast cancer screening, with a minimum delay of 8 years after radiotherapy, or * with a significant irradiation dose to the breast (Irradiation that delivered at least 10 Gy on at least part of the breast (v 5\> 10 Gy) or on the mammary bud (v 100\> 10 Gy) - (centrally validated dose) or received TBI (Total Body Irradiation)\> 8 Gy according to a bi-fractioned scheme or\> 6 Gy in single dose) +Inclusion criteria for thyroid screening: * being a man or a woman and being 18 years or more for thyroid cancer screening with a minimum delay of 5 years after radiotherapy, and, * with a significant irradiation dose to the thyroid (Irradiation having delivered at least 3 Gy on the thyroid (v100\> 3 Gy), or having received a TBI (Total Body Irradiation)\> 2 Gy, and / or treatment with 131i-metaiodobenzylguanidine), and Exclusion Criteria: * life expectancy \<10 years due to other pathology * patient in regular follow-up within the framework of a genetic susceptibility (ex li fraumeni) * person placed under safeguard of justice \+ exclusion criteria for breast cancer screening : * patient treated with bilateral mastectomy, or * patient being treated for breast cancer, or * patient initially treated with radiotherapy for breast cancer \+ exclusion criteria for breast cancer screening : * Thyroidectomy, or * patient undergoing treatment or with a personal history of thyroid cancer
References
Publications (0)
Data not yet available