Clinical trial · Observational
IRM Cognition in Patients With Head Trauma
Longitudinal Descriptive Study of the Correlation Between Cognitive Functions, White Matter Anatomical Pathways and Functional Magnetic Resonance Imaging Activations in Patients With Moderate to Severe Head Trauma.
NCT03181373CI-TRIAL-00028042unknownClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Longitudinal descriptive study of a cohort of twenty brain-damaged patients for a two years period.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain-damaged Patients | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Cognitive rehabilitation program | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Traumatic brain injury population
- description
- Defined population : traumatic brain injury population
- interventionNames
- Other: Cognitive rehabilitation program
Primary outcomes (1)
- measure
- Changes in Baseline standardized volume of the white matter fascicles
- timeFrame
- at 3, 12 and 24 months
- description
- determined on the "iplan" software. Baseline measured at 3 months after brain traumatic injury.
Secondary outcomes (2)
- measure
- Measure of the volume of activations clusters
- timeFrame
- at 3, 12 and 24 months
- description
- during functional MRI for attention, motor, working memory, language tasks.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients, over the age of 18. * Mild traumatic brain injury (Initial Glasgow score between 9 and 12) * Severe brain injury (Initial Glasgow score between 3 and 8), * Diffuse axonal injury and/or focal lesions. Exclusion Criteria: * Patients with MRI contraindications, * Antecedents of brain lesions, * Important lesions of the lobes and cortex on cerebral CT, * Anoxic lesions related to cardiorespiratory arrest, * Must be able to perform neuropsychological tests, * Visual and auditory impairments. * Aphasia
References
Publications (0)
Data not yet available
No reference posted for this study.