Clinical trial · Observational
Early Detection of Lung Cancer
Early Detection of Lung Cancer in the Medically Underserved Population
NCT03181256CI-TRIAL-00110485active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This research trial studies the long term follow-up for early detection of lung cancer in current or former smokers. Following up on smokers by collecting and analyzing specimens in the laboratory, performing chest computed tomography (CT) scans, as well as reviewing medical records may help doctors detect lung cancer at an earlier stage.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (4)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biospecimen Collection | Procedure | — | UNRESOLVED |
| Computed Tomography (CT) | Procedure | — | UNRESOLVED |
| Laboratory Biomarker | Other | — | UNRESOLVED |
| Pulmonary Function Test | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Screening
- description
- Patients are followed up at 1, 2, 3, 4, and 5 years and undergo collection of sputum, nasal epithelium, buccal epithelium, blood, and urine samples. Patients also undergo pulmonary function tests, chest CT, and review of medical records
- interventionNames
- Procedure: Biospecimen Collection
- Procedure: Pulmonary Function Test
- Procedure: Computed Tomography (CT)
- Other: Laboratory Biomarker
Primary outcomes (1)
- measure
- Candidate biomarkers of risk or of early diagnosis
- timeFrame
- Up to 5 years.
- description
- Will validate the performance of the candidate biomarkers of risk or of early diagnosis.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 55 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: * Current smoker or former smoker, if former smoker participants must have quit smoking within the past 15 years * \>= 30 pack year of smoking history * Participant is uninsured Exclusion Criteria: * History of diagnosis/treatment of lung cancer in the past 2 years * History of head/neck or esophageal cancer in the last 1 year * Inability to provide informed consent
References
Publications (0)
Data not yet available
No reference posted for this study.