Clinical trial · Interventional
Carbon Dioxide Laser and Cryotherapy in Treatment of Warts
Comparative Evaluation of Carbon Dioxide Laser and Cryotherapy by Dermoscopy in Treatment of Viral Wart
NCT03166137CI-TRIAL-00027798unknownN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Viral warts are common skin conditions seen in both children and adults. Human papilloma virus is responsible for verrucae. Cutaneous manifestation of the human papillomavirus, are extremely common particularly on the hands and feet. Warts can induce hard, thickened skin, black pinpoints, pain or tenderness with significant morbidity for the patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Common Warts | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Carbon dioxide laser | Device | — | UNRESOLVED |
| Cryotherapy | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Carbon dioxide laser group
- description
- (group A): thirty patients will be treated by application of carbon dioxide laser.
- interventionNames
- Device: Carbon dioxide laser
- type
- ACTIVE_COMPARATOR
- label
- Cryotherapy group
- description
- (group B): thirty patients will be treated by cryotherapy application.
- interventionNames
- Device: Cryotherapy
Primary outcomes (1)
- measure
- Number and size of the lesions.
- timeFrame
- Two months
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: 1. Patients with common warts male or females any age. 2. Patient is able to read and understand English and will give written informed consent to participate. 3. Patient elects to undergo carbon dioxide laser therapy or cryotherapy for treatment of common warts. 4. Warts to be treated will be located only on the hands. Exclusion Criteria: 1. Non cooperative patients. 2. Patients on other lines of treatment. 3. Pregnant and lactating females. 4. Patients receiving topical treatment in the previous two weeks. 5. Secondary infection.
References
Publications (4)
- RESULTVlahovic TC, Khan MT. The Human Papillomavirus and Its Role in Plantar Warts: A Comprehensive Review of Diagnosis and Management. Clin Podiatr Med Surg. 2016 Jul;33(3):337-53. doi: 10.1016/j.cpm.2016.02.003. Epub 2016 Mar 29. PMID 27215155
- RESULTKwok CS, Gibbs S, Bennett C, Holland R, Abbott R. Topical treatments for cutaneous warts. Cochrane Database Syst Rev. 2012 Sep 12;2012(9):CD001781. doi: 10.1002/14651858.CD001781.pub3. PMID 22972052
- RESULTAndrews MD. Cryosurgery for common skin conditions. Am Fam Physician. 2004 May 15;69(10):2365-72. PMID 15168956
- RESULTZalaudek I, Giacomel J, Cabo H, Di Stefani A, Ferrara G, Hofmann-Wellenhof R, Malvehy J, Puig S, Stolz W, Argenziano G. Entodermoscopy: a new tool for diagnosing skin infections and infestations. Dermatology. 2008;216(1):14-23. doi: 10.1159/000109353. PMID 18032894