Clinical trial · Observational
Functional ImaGing of Heterogeneity in Head and Neck Tumors - Validation From Surgical Specimens
NCT03160495CI-TRIAL-00037777FIGHHTcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to investigate if heterogeneity in head and neck squamous cell carcinoma as seen in functional imaging with PET/MR can be correlated to biologic heterogeneity in surgical specimens.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Squamous Cell Carcinoma of the Head and Neck | Head and Neck Squamous Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| All patients | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (3)
- measure
- Quantified measures from FDG PET and pathology
- timeFrame
- 3-6 months
- description
- Correlation between FDG uptake (measured as SUV) and expression of IHC biomarkers
- measure
- Quantified measures from DWI and pathology
- timeFrame
- 3-6 months
- description
- Correlation between diffusion weighted imaging and expression of IHC biomarkers
- measure
- Quantified measures from DCE and pathology
- timeFrame
- 3-6 months
- description
- Correlation between dynamic contrast enhancement and expression of IHC biomarkers
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Informed consent * Age above 18 * Primary or recurrent squamous cell carcinoma in the head and neck area * Referred to surgery * Primary tumor \> 1.5 cm and or neck metastasis of more than 1 cm. Exclusion Criteria: * Patient refusal * Contraindications for FDG-PET/MR scan * Pacemaker * Severe claustrophobia * Magnetic metal in the body that is not MR compatible
References
Publications (0)
Data not yet available
No reference posted for this study.