Clinical trial · Observational
Ultra-Low Dose CT Denoising for Lung Nodule Detection
NCT03159377CI-TRIAL-00054484completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
We will perform an ultra low-dose CT (ULDCT) in addition to a regular chest CT scan for adult patients undergoing a clinically indicated chest CT. Using a recently developed computationally efficient algorithm for the denoising of ULDCT scans after image reconstruction, we will compare the sensitivity, specificity and accuracy of lesion detection with the ULDCT as compared to the regular CT scan.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pulmonary Nodule, Multiple | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Ultra low dose chest CT | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Patients scheduled for a chest CT
- description
- Inpatients or outpatients scheduled for a chest CT in our medical center
- interventionNames
- Device: Ultra low dose chest CT
Primary outcomes (1)
- measure
- Identification of a pulmonary nodule
- timeFrame
- Patient collection in two years
- description
- Comparison of sensitivity, specificity and accuracy in identifying a pulmonary nodule when comparing denoised ULDCT to a regular CT.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 110 Years
Show eligibility criteria text
Inclusion Criteria: * Any adult patient scheduled for a chest CT, in-patient or outpatient Exclusion Criteria: * Children
References
Publications (0)
Data not yet available
No reference posted for this study.