Clinical trial · Observational
MMP-7 Modulation by Short and Long Term Radiotherapy in Rectal Cancer Patients
Effect of Long and Short Radiotherapy on MMP-7 Levels in Rectal Cancer Treatment
NCT03151759CI-TRIAL-00027540MMP-7completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To analyse the effects of radiation therapy on inflammation and matrilysin levels in rectal cancer patients.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Neoadjuvant radiotherapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- No radiotherapy
- description
- Surgery only
- label
- 25 Gray radiotherapy
- description
- Surgery after short term radiotherapy
- interventionNames
- Radiation: Neoadjuvant radiotherapy
- label
- 50 Gray radiotherapy
- description
- Surgery after long term radiotherapy
- interventionNames
- Radiation: Neoadjuvant radiotherapy
Primary outcomes (1)
- measure
- Matrilysin levels
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: Adenocarcinoma of the rectum, ability to understand written and oral information, written consent. Exclusion Criteria: Colon cancer, benign tumors, impaired general condition of patient, declining to participate in the study, synchronous colonic tumors, logistical reasons, inability to understand written and/or oral information, previous pelvic irradiation, ongoing immunosuppressive therapy, diabetes with systemic complications.
References
Publications (0)
Data not yet available
No reference posted for this study.