Clinical trial · Observational
Hypermetabolism in the Elderly Lung Cancer Patient
NCT03141957CI-TRIAL-00027416HELPcompletedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Aging and cancer are two conditions associated with extensive metabolic changes that can cause malnutrition. However, the clinical features and the underlying mechanisms leading to malnutrition are different in these two cases. We therefore wonder how age can influence the metabolic response to cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Non-small Cell Lung Carcinoma | Lung Non-Small Cell Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (2)
- label
- Young patients
- description
- Patients with non-small cell lung carcinoma younger than 75y
- label
- Elderly patients
- description
- Patients with non-small cell lung carcinoma aged 75 or more
Primary outcomes (1)
- measure
- Measured resting energy expenditure (mREE) in kilocalorie per day
- timeFrame
- Day 0
- description
- Energy expenditure is measured by indirect calorimetry.
Secondary outcomes (14)
- measure
- Blood C-Reactive Protein in milligram per milliliter
- timeFrame
- Day 0
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 95 Years
Show eligibility criteria text
Inclusion Criteria: * Non-small cell lung carcinoma Exclusion Criteria: * Imbalanced Diabetes * Imbalanced dysthyroidia * Surgery within two month prior inclusion * Any chronic auto-immune or inflammatory disease
References
Publications (1)
- DERIVEDUlmann G, Jouinot A, Tlemsani C, Curis E, Kousignian I, Neveux N, Durand JP, Goldwasser F, Cynober L, De Bandt JP. Lean Body Mass and Endocrine Status But Not Age Are Determinants of Resting Energy Expenditure in Patients with Non-Small Cell Lung Cancer. Ann Nutr Metab. 2019;75(4):223-230. doi: 10.1159/000504874. Epub 2019 Dec 19. PMID 31865308