Clinical trial · Observational
Multimodal Assessment of Liver Volume and Function
Multimodal Assessment of Liver Volume and Function in Patients With Colorectal Liver Metastases
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In liver surgery peroperative assessment och the future liver remnant (FLR) is pivotal in order to avoid posthepatectomy liver failure. To date this is mainly performed by measuring the volume of the FLR. Of course FLR volume acts as a surrogate measure of FLR function and the correlation between volume and function is not always accurate. Several techniques to assess FLR function has been proposed. Hepatobiliary scintigraphy (HBS) and Dynamic MRI are the two such methods. In this study we compare HBS and MRI, in addition to contrast-enhanced CT and ICG, repeatedly performed before and after right hepatectomy in patients with colorectal liver metastases treated with neoadjuvant chemotherapy.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
| Liver Metastases | Colorectal Neoplasm | PROBABILISTIC | 0.70 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Multimodal liver function assessment | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Correlation between HBS and MRI in assessment of FLR function preop
- timeFrame
- Preop
- description
- HBS, MRI, CT and ICG performed the day before surgery
Secondary outcomes (2)
- measure
- Correlation between HBS and MRI in assessment of FLR function POD 7
- timeFrame
- POD 7
- description
- HBS, MRI, CT and ICG performed 7 days after surgery
- measure
- Correlation between HBS and MRI in assessment of FLR function POD 28
- timeFrame
- POD 28
- description
- HBS, MRI, CT and ICG performed 28 days after surgery
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * CRLM treated with neoadjuvant chemotherapy subjected to right hepatectomy Exclusion Criteria: \-
References
Publications (0)
Data not yet available