Clinical trial · Observational
The Cardiovascular Changes Associated With Septal Local Anaesthesia
An Observational Study of the Cardiovascular Response to Infiltration of Local Anaesthetic Into the Nasal Septum in Patients Undergoing Trans-sphenoidal Resection of a Pituitary Lesion
NCT03137615CI-TRIAL-00027350completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine the effects on the heart of injecting local anaesthetic into the nose prior to surgery on the pituitary gland?
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anesthesia, Local | — | UNRESOLVED | — |
| Hypothalamic Neoplasms | Hypothalamic Neoplasm | ONTOLOGY_EXACT | 0.98 |
| Pituitary Diseases | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| local anaesthetic injection | Drug | — | UNRESOLVED |
| Pituitary surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Pituitary Surgery
- description
- Patients having pituitary gland surgery Inclusion criteria - Any adult patient undergoing trans-sphenoidal pituitary surgery. Exclusion criteria - Under 16 years of age, pregnancy, uncontrolled hypertension, allergy to any local anaesthetic, patient refusal or revision pituitary surgery
- interventionNames
- Procedure: Pituitary surgery
- Drug: local anaesthetic injection
Primary outcomes (1)
- measure
- Change in blood pressure after administration of local anaesthesia
- timeFrame
- 5 minutes
- description
- Changes in mean arterial pressure from baseline after infiltration of local anaesthetic.
Secondary outcomes (3)
- measure
- Change in heart rate after administration of local anaesthesia
- timeFrame
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 17 Years
Show eligibility criteria text
Inclusion Criteria: * Any adult patient undergoing trans-sphenoidal pituitary surgery. Exclusion Criteria: * Under 16 years of age, pregnancy, uncontrolled hypertension, allergy to any local anaesthetic, patient refusal or revision pituitary surgery.
References
Publications (0)
Data not yet available
No reference posted for this study.